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Sandesh J. Marathe

Sandesh earned his Ph.D. in Biotechnology in 2020, from the Institute of Chemical Technology, Mumbai. His Ph.D. research focused on enzymatic biotransformation of sugars and polyphenols to enhance functionality. Sandesh is currently a Postdoctoral Researcher at the University of Tennessee Health Science Center (UTHSC), Memphis, US. His research interests include immunology, pharmacognosy, food bioscience, and functional foods and he is passionate about scientific writing.

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Articles by Sandesh J. Marathe

Image of eggs, one with a helmet and another getting hit by a hammer to express the dos and don'ts of CAM assays

6 Dos and Don’ts for Perfecting the CAM Assay

By Sandesh Marathe | October 22, 2020

Don’t put all your eggs in one basket! Learn how to handle your eggs, prevent contamination and keep track of your experiments when performing the CAM assay.

A graphic depicting various aspects of science education to highlight PhD vs Master's Degrees

PhD vs Master’s: Which to Choose?

By Sandesh Marathe | September 30, 2020

If choosing between a PhD or a Master’s has you frazzled, don’t panic. We weigh the pros and cons of both in terms of time, money, and career prospects.

Hand holding a brown egg to depict using chick embryps for studying angiogenesis

Chick Embryo: A Model System for Studying Angiogenesis

By Sandesh Marathe | September 23, 2020

Are you studying angiogenesis? Is cell culture not cutting it but you’re not ready for an in vivo model? Check out the CAM assay.

A man with a red tie and red cape standing proudly.

Excelling With Excel: Analytical Method Validation Using LOD and LOQ

By Sandesh Marathe | August 28, 2020

Don’t be fooled by bad data. Make sure your results are reliable with this quick guide to determining LOQ and LOD in Excel.

How to Maintain Motivation in the Lab During an Existential Crisis

How to Maintain Motivation in the Lab During an Existential Crisis

By Sandesh Marathe | August 17, 2020

How does one maintain the motivation to get out of the bed, do all the lab work, bear the supervisor and the colleagues one doesn’t gel with, and also maintain personal life? Here are a few ways to deal with stress and maintain motivation.

Checklist depicting list of dos and don'ts

The Do’s and Don’ts of HPTLC 

By Sandesh Marathe | June 18, 2020

This followup article on HPTLC gives a list of dos and don’ts while performing HPTLC to achieve precise and error-free results, and avoid false positives.

Toy robot indicating automation and robotic capacity of HPTLC as compared to TLC

HPTLC: Basics and Instrumentation

By Sandesh Marathe | June 11, 2020

Get robotic with HPTLC! This automated version of TLC can separate and quantify compounds – find out how!

troubleshooting thin layer chromatography

Troubleshooting Thin Layer Chromatography: Some TLC for Your TLC

By Sandesh Marathe | July 26, 2016

The whole TLC technique sounds easy to do, but it can be difficult and tricky during interpretation or give unexpected results, especially when working with biomolecules. For this reason, it is important to be familiar with troubleshooting thin layer chromatography. Some of the common problems faced during TLC and their solutions are listed below: Solvent…

uses of thin layer chromatography

The Many Uses of Thin Layer Chromatography

By Sandesh Marathe | July 9, 2016

While working as biologists, we often come across mixtures of compounds, and the first question that strikes our minds is ‘what are the components in this mixture?’ One might think of using chemical assays to find the presence of specific compounds. But that sounds painful, doesn’t it? Well, the good news is that thin layer…

thin layer chromatography

Thin Layer Chromatography: The Basics

By Sandesh Marathe | July 9, 2016

Like most other chromatographic techniques, thin layer chromatography (TLC) separates out individual compounds from a mixture depending upon the polarity of each compound. The solvent system travels up a silica plate by capillary action and passes over the sample that you spot onto the plate. As the solvent travels up, it moves the compounds present…

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