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Cells and Model Organisms

Pop Quiz!: Do You Know How a Coulter Counter Works?

Are you an immunologist or lab personnel dealing with counting tons of cells? Then you must have come across the elusive Coulter Counter! Read on to know a little history ofthe instrument’s technology and its working principle.

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The Culture of Primary Schwann Cells  

Have you been itching to branch into working with Schwann cells for your next experiment, but aren’t quite sure where to begin? This article will help you decide which primary Schwann cell line is best for your needs.

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Tips for Successful Bone Marrow Isolation 

During my first year of graduate school, I learned how to isolate bone marrow. I remember watching my mentor in awe, wondering how would I be able to do such a difficult technique. Flash forward to a few weeks later and I was confidently undertaking bone marrow isolation. Learning a new technique is always daunting,…

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Culturing M1 and M2 Macrophages: Media Matters

Macrophages are a type of white blood cell derived from monocytes that are most widely known for the ability to phagocytose cell debris, pathogens, and even cancer cells. However, it is becoming clear that the role of macrophages goes beyond eliminating cellular waste. Macrophages are often used in conjunction with T cells to measure immune…

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The What, Why and How of Explant Culture

What Is Explant Culture and Why Should I Use It? Explant culture is the culture of small pieces of tissue surgically removed from animal tissue or organ. It is a useful method for several reasons. The maintenance of the histotypic architecture and biochemical properties of the cells means it more closely resembles the tissue in…

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