Microscopy and Imaging
The Ultimate Guide to Choosing a Fluorescent Protein
Discover the critical considerations when choosing a fluorescent protein, the key features of those most commonly used, and why newer might be better.
Read MoreHigh-resolution 3D imaging uncovers vascular control of tissue ageing
High-resolution 3D imaging uncovers vascular control of tissue ageing Wednesday 15th September 2021LONDON 16:00 BST | BERLIN 17:00 CET | DUBAI 19:00 GST Ageing is associated with alterations in tissue homeostasis and a decline in tissue functions. Blood vessels provide supportive microenvironments for various cell types to maintain tissue homeostasis and organ function. However, ageing…
Read MoreIn the right place at the right time: How to successfully implement the Leica Nano workflow
In the right place at the right time:How to successfully implement the Leica Nano workflow Tuesday September 7th 2021LONDON 15:00 BST | BERLIN 16:00 CET | DUBAI 18:00 GST Many electron microscope (EM) workflows start with sample fixation, followed by sample preparation and EM imaging. However, samples displaying interesting behavior tend to be rare, and…
Read MoreAn Introduction To Fixation For Histology: Think Before You Fix!
How you fix your tissue or cells can affect your results, for better or for worse. Discover the key points to think about before undertaking your histology fixation.
Read MoreA (very) Short History of Histology
Discover the history of histology, from the first mention of a cell in 1665 to the identification and development of various stains.
Read MoreAvoid These Pitfalls: Seven (Not So Deadly) Histology Sins
Discover seven common histology mistakes and how you can avoid making them when performing your experiments.
Read MoreAutomating IHC and RNAscope® ISH for academic research: Insights from equine arteritis virus and COVID-19
Automating IHC and RNAscope® ISH for academic research: Insights from equine arteritis virus and COVID-19 Available On Demand Speaker Dr. Mariano Carossino DVM, PhD, Dipl. ACVM Assistant Professor (appointed) Department of Pathobiological Sciences & Louisiana Animal Disease Diagnostic LaboratoryLouisiana State University, School of Veterinary Medicine Dr. Mariano Carossino is an Assistant Professor at the Louisiana…
Read MoreThat Other Number – The Meaning Of Numerical Aperture In Microscopy
Do you know what that NA number is on your objective? We walk you through what the numerical aperture is and why it’s important.
Read MoreAn Objective View: What do These Abbreviations Mean on Microscope Objectives?
There are a large number of microscope objective abbreviations relating to optical aberrations; here we’ll shed some light on some of the most common ones to get you up to speed in no time!
Read MoreLive Imaging of Phagocytosis: Your Simple Guide to Capturing the Action
Live imaging of phagocytosis helps capture the details of this dynamic process. Discover tips and tricks to visualizing this important cellular process.
Read MoreSee The Hidden: Artificial Intelligence in Microscopy
See The HiddenArtificial Intelligence in Microscopy Available On-Demand Introduction to AI for Microscopists: all you need to know Machine and deep learning technologies already play a major role in everyday life – think Alexa, Tesla’s Autopilot, Spotify, Amazon or YouTube. In the last 3 years, microscopists have started to use “AI based” solutions for image…
Read MoreA Beginner’s Guide to The Point Spread Function
Learn how the Point Spread Function affects what you see through your microscope and discover what you can do to improve your images.
Read MoreIntravital Microscopy of Cancer
Intravital Microscopy of Cancer Available on Demand In this webinar, you will learn: about intravital microscopy techniques that allow you to monitor stem cells and cancer cells in real-time in vivo; how these techniques can help you study the identity and migratory behavior of cancer stem cells; how intravital microscopy uses multiphoton confocal microscopy to…
Read MoreOptimal Conditions for Live-Cell Imaging
Live-cell imaging can bring a lot of clarity to cellular processes, but keeping your cells happy can be tricky. Read on to learn about 4 key parameters for achieving optimal conditions for live-cell imaging.
Read MoreAn Introduction to Live Cell Imaging
Read on to learn more about live cell imaging, including how high rate microscopy can help you capture rapid cellular processes.
Read MoreVisualising protein degradation and aggregation in the living cell
Visualising protein degradation and aggregation in the living cell Available On Demandat MicroscopyFocus.com Watch Now In this webinar, Prof. Eric Reits will discuss how several neurodegenerative disorders, including Alzheimer’s, Parkinson’s and Huntington’s disease, are characterized by the formation of protein aggregates, and that components of the ubiquitin-proteasome system (UPS) co-localize in these aggregates. This has…
Read MoreLife beyond the pixels: deep learning methods for single cell analysis
Life beyond the pixels:Deep learning methods for single cell analysis Available On Demand In this webinar, you will discover: the computational steps in the analysis of single cell-based large-scale microscopy experiments; a novel microscopic image correction method designed to eliminate illumination and uneven background effects; new single-cell image segmentation methods; the Advanced Cell Classifier, a…
Read MoreHow History Shaped Modern Optical Microscopes, Part Two: Corrected Lenses and Objectives
Discover how chromatic and geometric imaging aberrations have been corrected over the last few centuries with the development of corrected lenses and objectives.
Read MoreSee The Hidden: Virtual Neurosciences Workshop
See The Hidden: Virtual Neurosciences Workshop This live online event brings together a series of scientific talks and microscopy showcases, centering around four specific topics in microscopy – 3D real time imaging*, laser microdissection, confocal nanoscopy and high pressure freezing techniques in electron microscopy. Each section will kick off with a scientific talk from one…
Read MoreHow History Shaped Modern Optical Microscopes, Part One: Simple and Compound Microscopes
Discover the history of simple and compound microscopes in this first of our two-part series on the history of microscopes.
Read MoreAdvanced Sectioning Techniques: How to Section Difficult Tissues
Are you having problems with tissue sectioning? Follow these 10 tissue sectioning tips to create the perfect tissue section every time without stressing out.
Read MoreStereo (Dissecting) Microscopes 101
Want to know about stereo microscopes? This article answers what a stereo microscope is, how it works and why it’s a great tool for biologists!
Read MoreUltraMicroscope Blaze™ live instrument demonstration
UltraMicroscope Blaze™ live instrument demonstration Available On-Demand Register & Watch Now This live demonstration introduces you directly to the Ultramicroscope Blaze, a fully-automated, multi-scale, high-resolution, light sheet imaging system for high throughput volumetric imaging of large biological samples. Our imaging team will demonstrate the ease-of-use and performance of the instrument and take you through the…
Read MoreThe UltraMicroscope Blaze™: Automated 3D imaging on an unprecedented scale
The UltraMicroscope Blaze™: Automated 3D imaging on an unprecedented scale Available On-Demand Register & Watch Now This webinar introduces the brand new Ultramicroscope Blaze. This next-generation light sheet imaging system brings together more than a decade of light sheet fluorescence microscopy (LSFM) development and collaboration. The Blaze is a fully-automated light sheet imaging system with,…
Read MoreMesoscopic Whole-Organ Imaging: Experimental Models and Diagnostic Potential
Mesoscopic Whole-Organ Imaging: Experimental Models and Diagnostic Potential Available On-Demand Register & Watch Now Cellular interactions and thus organ function and anatomy are inherently of a three-dimensional (3D) nature. Knowledge of the cellular distribution patterns within organs, in both health and disease states, is critical to our understanding of ongoing microscopic processes on a mesoscopic…
Read MoreConfocal Images: Expert Tips for Your Hour of Need!
Getting publication perfect confocal images can be tricky. If you are struggling or just want to ensure you’re capturing the best images possible, check out our top 7 tips for confocal imaging.
Read MoreResolution and Refractive Index: Set-up Your Confocal Wisely!
Get the best out of your time on the microscope by understanding the refractive index of your experiment to optimize and increase your resolution.
Read MoreFun With FRAP! Fluorescence Recovery After Photobleaching for Confocal Microscopy
If you’re thinking FRAP is short for frappuccino then you need to read this article. Discover the history, how it works, and why you’d want it in your confocal toolbox
Read MoreExploring The Structure and Life Cycle of Viruses
Exploring The Structure and Life Cycle of Viruses The Virologist’s Toolbox for Electron Microscopy Specimen Preparation Available On Demand Speakers Frédéric Leroux Advanced Workflow SpecialistLeica Microsystems Frédéric Leroux completed his Master degree in Biology in 2007 at the University of Ghent where he gained experience in biological EM sample preparation. In 2008, he moved to…
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Ask Eric Anything
A live episode of The Microscopists featuring Eric Betzig
Ask Eric Anything A live episode of The Microscopists featuring Eric Betzig On-Demand Ask Eric Anything: A live episode of The Microscopists featuring Eric Betzig On-Demand The Microscopists is going LIVE! For a one-off and very special guest – Eric Betzig! We already know so much about Eric, but I hope that our chat will…
Read MoreAn introduction to Photoactivated Localization Microscopy (PALM)
How does photoactivated localization microscopy (PALM) work? And what use can PALM microscopy be to you? This short introduction to PALM gives you the answers!
Read MoreBeginners Guide to PALM Sample Preparation
Good PALM sample preparation is the key to great images. Find out how to choose the right fluorescent proteins and learn some tips and tricks for sample prep.
Read MoreTurn a Smartphone into a Digital Microscope for Only 3 Cents
Want to build your own microscope for almost nothing? You probably already have most of the tools that you need right in your lab or at home! Here’s how.
Read MoreTrapping Objects With Light: From Star Wars to Neurons
Can lasers be used to trap and move objects? Sure they can! Read on to know how you can use lasers in a cool technique called optical tweezers to manipulate minuscule objects under the microscope.
Read MoreHow Histology Slides are Prepared
Ever wondered what magic happens to turn your samples into histology slides? Find out the 5 simple steps for histology slide preparation.
Read MoreTissue Processing For Histology: What Exactly Happens?
Tissue processing for histology is a key step between fixation and embedding. We take you through the steps of tissue processing in this simple guide.
Read MoreThe Dilemma of Live Cell Imaging – How to See Something That Does not Like Light
Don’t get overexcited but we’ve got 7 top tips to help you minimize photodamage during your fluorescent live-cell imaging experiments.
Read MoreHow to Measure Myelin Thickness Manually (and Other Tedious Lab Tasks) and Keep Your Sanity
Tips on staying sane from a student survivor of tedious lab tasks.
Read MoreFrom Organs to Tissues to Cells: Analyzing 3D Specimens with Widefield Microscopy
From Organs to Tissues to Cells: Analyzing 3D Specimens with Widefield Microscopy On Demand Speakers Dr. Falco Krüger Advanced Workflow Specialist Widefield Life Science Research DivisionLeica Microsystems Falco did his PhD in Biology at the Plant Cell Biology chair of Prof. Karin Schumacher at the Centre for Organismal Studies (COS) in Heidelberg, Germany. For his…
Read MoreRevealing functional mechanisms of synaptic transmission by high-pressure freezing
Revealing functional mechanisms of synaptic transmission by high-pressure freezing On Demand Speakers Frédéric Leroux Advanced workflow specialist, Leica Microsystems Frédéric Leroux completed his Master degree in Biology in 2007 at the University of Ghent where he gained experience in biological EM sample preparation. In 2008, he moved to the physics department at the University of…
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