Navigating the “Cs” Part 1: an Introduction to Chromatin Conformation Capture Techniques
Interest in the three-dimensional structure of chromatin has exploded over the past few years—and for good reason! We now know that DNA isn’t randomly piled into the nucleus like a bowl of spaghetti, but arranged in functional loops and domains, more like a city blueprint. This is particularly exciting to (epi)genomic scientists, because 3D chromatin…
