Techniques
Trapping Objects With Light: From Star Wars to Neurons
Can lasers be used to trap and move objects? Sure they can! Read on to know how you can use lasers in a cool technique called optical tweezers to manipulate minuscule objects under the microscope.
Read More Troublesome Site-Directed Mutagenesis: Troubleshooting Your Experiment for Stubborn Mutations
As is sadly the case in many experiments, site-directed mutagenesis (SDM) does not always work the way we would like it to the first time around. Here are a few tips to help you on your way when trying to troubleshoot a bothersome SDM reaction!
Read More How Histology Slides are Prepared
Ever wondered what magic happens to turn your samples into histology slides? Find out the 5 simple steps for histology slide preparation.
Read More What Is a Cq (Ct) Value?
Don’t stay confused by Ct values! We’ll guide you through what they are, how to calculate them, and troubleshooting issues.
Read More CRISPR Screening: from design and discovery to validation
CRISPR Screening: from design and discovery to validation Date: Wednesday 9th December 2020Broadcast 1: 9 am Moscow, 11.30 am Delhi, 2 pm Beijing, 3 pm TokyoBroadcast 2: 4 pm London, 5 pm Berlin, 8 am Los Angeles, 11 am New York Speaker Gillian Browne, PhD Global Head of Commercial Enablement, Genome Engineering & ModulationMilliporeSigma Gillian received…
Read More Tissue Processing For Histology: What Exactly Happens?
When preparing a sample (or multiple samples) for histology microscopy, there are multiple steps required. We’ve covered these steps in brief in a previous article on How Histology Slides are Prepared, but this article will focus on one particular procedure that needs to take place between tissue fixation and the embedding/sectioning of paraffin blocks: tissue…
Read More Get a Move On: How to Measure Movement in Zebrafish
If you are interested in the sensory or motor function of your zebrafish model, this is the test to try.
Read More The Dilemma of Live Cell Imaging – How to See Something That Does not Like Light
Don’t get overexcited but we’ve got 7 top tips to help you minimize photodamage during your fluorescent live-cell imaging experiments.
Read More How to Measure Myelin Thickness Manually (and Other Tedious Lab Tasks) and Keep Your Sanity
6 Dos and Don’ts for Perfecting the CAM Assay
Don’t put all your eggs in one basket! Learn how to handle your eggs, prevent contamination and keep track of your experiments when performing the CAM assay.
Read More Optimizing CRISPR mouse model pipelines – modified synthetic sgRNAs
Optimizing CRISPR mouse model pipelines – modified synthetic sgRNAs On Demand Speaker Matthew Mackenzie Resource Support ManagerMRC Harwell Matthew Mackenzie earned a BSc in Genetics at the University of Liverpool, where he spent a year in industry with LGC Forensics (now Eurofins) gaining insights into high-throughput sample analysis and automation. After graduating in 2015 he…
Read More Detecting Post-Translational Modifications
Preparing Metaphase Spreads: The Breakdown on Broken-Down Cells
A quick look at the first steps of metaphase spreads – the break down on breaking down your cells and the factors to keep in mind.
Read More A-Z of Post-Translational Modifications
You might know the most common post-translational modifications, but there are many more than just phosphorylation and ubiquitination – come and test your knowledge!
Read More From Organs to Tissues to Cells: Analyzing 3D Specimens with Widefield Microscopy
From Organs to Tissues to Cells: Analyzing 3D Specimens with Widefield Microscopy On Demand Speakers Dr. Falco Krüger Advanced Workflow Specialist Widefield Life Science Research DivisionLeica Microsystems Falco did his PhD in Biology at the Plant Cell Biology chair of Prof. Karin Schumacher at the Centre for Organismal Studies (COS) in Heidelberg, Germany. For his…
Read More Synthetic Peptides and Their Uses: Part 1
Are you studying a small peptide or protein? Learn whether using synthetic peptides can save you hours of transfection, protein expression, and purification.
Read More An Experimental Toolkit for Measuring Autophagic Flux
How good is your cell at recycling? In this guide, we explain what autophagic flux is, why you need to study it, and methods to get you started.
Read More Becoming a Patch Clamping Pipette Wizard
Is patching clamping a problem? Struggling to get a good seal? There is no need to stress! We’ve got tips on picking and preparing the perfect pipette for your patch clamping experiment!
Read More Chick Embryo: A Model System for Studying Angiogenesis
Are you studying angiogenesis? Is cell culture not cutting it but you’re not ready for an in vivo model? Check out the CAM assay.
Read More Chemically Induced Mouse Models – Where Consistency Matters
Tips and tricks to get the most optimum and consistent results in a DSS-induced colitis model
Read More