Pros and Cons of CRISPR: Simple Tips for Weighing Up CRISPR for Genome Editing

Pros and Cons of CRISPR: Simple Tips for Weighing Up CRISPR for Genome Editing

While CRISPR offers vast applications in disease research and drug target identification, it’s not always the optimal choice for every scenario. Explore the main advantages and challenges of using CRISPR-Cas9 to determine if it’s the right fit for your project.

How To Fix Adherent Cells For Microscopy And Imaging

How To Fix Adherent Cells For Microscopy And Imaging

Adherent cell fixation is a crucial step in preparing cells for microscopy and imaging, ensuring that cellular structures are preserved for detailed analysis. Read our 8-step guide on how to effectively fix adherent cells to your microscope slides, including tips on sterilization, coating, and fixation methods, right here.

Plasmid vs. Genomic DNA Extraction: The Difference
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Plasmid vs. Genomic DNA Extraction: The Difference

Most experiments start with a piece of DNA—either plasmid DNA or genomic DNA. And your downstream uses for it dictate how much you need, what contaminants you can tolerate, and your extraction and purification methods. In this article, we explain the key differences between plasmid and genomic DNA extraction methods.

A Better Alternative to Immortalized Cells: Combining CRISPR and iPSCs

A Better Alternative to Immortalized Cells: Combining CRISPR and iPSCs

Investigating human diseases and genetic variation is complex, but CRISPR-edited induced pluripotent stem cells present a promising alternative to immortalized cell lines. This article delves into genome editing principles and offers practical steps for optimizing research techniques, ensuring more accurate and ethical studies.

A Beginner’s Guide to Protein Structure Prediction

A Beginner’s Guide to Protein Structure Prediction

Dive into the world of protein structure science, where AI is revolutionizing the field by offering accurate predictions and free, open-access tools. In this beginner’s guide, we’ll explore these groundbreaking tools, discuss their strengths and weaknesses, and examine the implications for traditional experimental methods like NMR and X-ray crystallography.