Gail Seigel's Profile

budget read on

Running your Lab on a Shoestring Budget

We live in challenging times for academic biomedical research. The success rates for research grants have declined precipitously over the years. Under these circumstances, it is never too soon to take proactive measures to protect your research budget in the event of a funding lapse. We usually know months ahead of time when grant support […]

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In Basic Lab Skills & Know-how 1st of February, 2017
polymers read on

Polymers as Secondary Antibodies for Immunohistochemistry

Have you ever thought about using polymers for your immunohistochemistry experiments? Take this simple quiz and find out if polymers may be right for you: I order biotinylated secondary antibodies for immunohistochemistry. Yes/No I use avidin/biotin complexes in my staining protocol. Yes/No I have to block endogenous biotin in my tissue samples to avoid heavy […]

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In Microscopy & Imaging 13th of September, 2016
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Commercialize Reagents for Fun and Profit

How long has it been since you checked your lab freezer? Remember that plasmid you designed? How about that cell line you developed that now sits idly in the vapors of a liquid Nitrogen tank? And the novel peptide or enzyme from a few years ago that remains buried in permafrost? It’s time to revisit […]

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In Cells and Model Organisms 14th of July, 2016
PCR Apps read on

Smartphone PCR Apps for PCR-On-The-Go

For the busy scientist, a Smartphone is more than just a Facebook and Instagram viewer. In the past few years, apps have been developed that can also allow you to use your phone or tablet to design PCR and qPCR experiments on the go.

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In PCR, qPCR and qRT-PCR 9th of July, 2016
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Kiss your samples goodbye: Outsourcing your Next-Gen experiment

Genomic Science has come a long way since the early days of Sanger sequencing in the 1970’s. Today, there are jazzy new sequencing technologies that include fragment analysis, epigenetic sequencing, RNA/transcriptome sequencing and Next Generation Sequencing (NGS). Increasingly these technologies are becoming more accessible, but they still require highly specialized (read: expensive) equipment. Unless your […]

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In Genomics & Epigenetics 9th of July, 2016