Techniques
Structured Illumination Microscopy (SIM) – An Introduction
Discover how structured illumination microscopy works can help you see things in greater detail.

Immune Responses in Severe COVID-19 Patients
Speaker Professor Dexi Chen, the Director of the Beijing Institute of Hepatology, present data on immune responses in severe COVID-19.

Making the Perfect Blood Smear
Stop wasting time throwing out slide after slide trying to create a readable blood smear. Read our how-to guide for creating the perfect blood smear slide.

What Can Electron Microscopy Do for You?
The electron microscope (EM) – where electrons, rather than photons, make the image – fell out of fashion for a while, but it has come back refreshed. Modern electron microscopes cost less, use less electricity, and are generally easier to maintain than the older models, so it is likely that you can get your hands on one. Read on to learn more about this technique, and how to implement it into your research.

Pop Quiz!: Do You Know How a Coulter Counter Works?
Are you an immunologist or lab personnel dealing with counting tons of cells? Then you must have come across the elusive Coulter Counter! Read on to know a little history ofthe instrument’s technology and its working principle.

Feeder Cells – the What, Why and How
Feeder cells – your solution to difficult-to-grow cell problems. Find out what they are, why to use them, and how.

Markerless and Scarless Microbial Genome Engineering
Markerless and Scarless Microbial Genome Engineering On Demand Webinar Speaker Erik Eastlund Principal Scientist, Gene Editing and Novel Modalities, Merck KGaA, Darmstadt, Germany Erik is a principal scientist for Gene Editing and Novel Modalities at Merck KGaA, Darmstadt, Germany. His group is focused on developing microbial genome engineering tools while also engaging in a microbiome…

Workflows and instrumentation for cryo-electron microscopy: an overview
Workflows and instrumentation for cryo-electron microscopy: an overview Now On Demand Speaker Frédéric Leroux Advanced workflow specialist, Leica Microsystems Frédéric Leroux completed his Master degree in Biology in 2007 at the University of Ghent where he gained experience in biological EM sample preparation. In 2008, he moved to the physics department at the University of…

Advice on Working With Mice in the Lab
Working with mice doesn’t have to be intimidating. Read these tips to help keep your mouse-based experiments running smoothly.

Your Checklist to Working With an Emerging Model Organism
Are you struggling to answer your research question using established models? Consider going rogue and switching to a non-model organism!

Infecting Eukaryotic Cells With Bacteria (On Purpose!)
Yes, you can infect your eukaryotic cells with bacteria on purpose! Find out why and how in this article that lists steps for successful and productive infections.

Selection Pressures: Alternatives to Antibiotics in Molecular Cloning
Want to reduce the use of antibiotics in the lab? Start with switching to alternative cloning methods that use alternative selection pressures.

Microscope Disinfection: A Quick Guide
Shared microscopes have the potential to get dirty and spread nasties between samples and users. Check out our quick guide on how to clean and disinfect your microscope.

What Does “N” Mean When Using Cell Lines?
If you’re confused about what N numbers mean for cell lines, you’re not alone. We explain it all and give you a guide on best practice.

Take a Stab at It! A Guide to Microinjection in Zebrafish
When microinjecting zebrafish, time is of the essence. Read these tips and tricks on how to prepare ahead of time and ensure a successful microinjection.

A Brief History of CRISPR-Cas9 Genome-Editing Tools
Learn how the CRISPR prokaryote immune response systems were first discovered and the development of the CRISPR-Cas9 gene-editing tool.

Level Up Your Drug Screening With CRISPR
The Do’s and Don’ts of HPTLC
This followup article on HPTLC gives a list of dos and don’ts while performing HPTLC to achieve precise and error-free results, and avoid false positives.

Efficient Generation of Gene-edited Mouse Models and Cell Lines Using Synthetic sgRNA
Efficient Generation of Gene-edited Mouse Models and Cell Lines Using Synthetic sgRNA On Demand Webinar Dr. Peter Romanienko Managing Director, Genome Editing Shared Resource, Rutgers-Cancer Institute of New Jersey Dr. Peter Romanienko obtained his PhD training from Cornell Graduate School of Medical Sciences/Sloan Kettering Institute working on DNA repair in Dr. Maria Jasin’s laboratory and…

HPTLC: Basics and Instrumentation
Get robotic with HPTLC! This automated version of TLC can separate and quantify compounds – find out how!
