Techniques
Preparing Metaphase Spreads: The Breakdown on Broken-Down Cells
A quick look at the first steps of metaphase spreads – the break down on breaking down your cells and the factors to keep in mind.

A-Z of Post-Translational Modifications
You might know the most common post-translational modifications, but there are many more than just phosphorylation and ubiquitination – come and test your knowledge!

From Organs to Tissues to Cells: Analyzing 3D Specimens with Widefield Microscopy
From Organs to Tissues to Cells: Analyzing 3D Specimens with Widefield Microscopy On Demand Speakers Dr. Falco Krüger Advanced Workflow Specialist Widefield Life Science Research DivisionLeica Microsystems Falco did his PhD in Biology at the Plant Cell Biology chair of Prof. Karin Schumacher at the Centre for Organismal Studies (COS) in Heidelberg, Germany. For his…

Synthetic Peptides and Their Uses: Part 1
Are you studying a small peptide or protein? Learn whether using synthetic peptides can save you hours of transfection, protein expression, and purification.

An Experimental Toolkit for Measuring Autophagic Flux
How good is your cell at recycling? In this guide, we explain what autophagic flux is, why you need to study it, and methods to get you started.

Becoming a Patch Clamping Pipette Wizard
Is patching clamping a problem? Struggling to get a good seal? There is no need to stress! We’ve got tips on picking and preparing the perfect pipette for your patch clamping experiment!

Chick Embryo: A Model System for Studying Angiogenesis
Are you studying angiogenesis? Is cell culture not cutting it but you’re not ready for an in vivo model? Check out the CAM assay.

Chemically Induced Mouse Models – Where Consistency Matters
Tips and tricks to get the most optimum and consistent results in a DSS-induced colitis model

Top 5 Things to Keep in Mind When Detecting Non-Histone Lysine Acetylation
Lysine acetylation isn’t just for histones. Read on to find out how to determine whether your favorite protein is lysine acetylated.

A guide to leveraging single cell CRISPR screens for deeper biological insights
A guide to leveraging single cell CRISPR screens for deeper biological insights On Demand Speakers Andrew Ravanelli, Ph.D. Senior R&D Scientist, Genome and Epigenome Editing, Merck KGaA, Darmstadt, Germany Andrew obtained his Ph.D. in Cell Biology from Duke University, where he used mouse and zebrafish models to dissect cellular mechanisms of early tissue formation. He…

Revealing functional mechanisms of synaptic transmission by high-pressure freezing
Revealing functional mechanisms of synaptic transmission by high-pressure freezing On Demand Speakers Frédéric Leroux Advanced workflow specialist, Leica Microsystems Frédéric Leroux completed his Master degree in Biology in 2007 at the University of Ghent where he gained experience in biological EM sample preparation. In 2008, he moved to the physics department at the University of…

Recombinant Protein Expression: How to Choose the Right Affinity Tag
Using the right affinity tag can make protein purification a breeze. Read more to find out which tag is right for you.

Size Analysis of High-Molecular-Weight DNA for Long-Read Sequencing
Discover how to check DNA quality for long-read sequencing using electrophoresis and why pipetting carefully is so important.

Structured Illumination Microscopy (SIM) – An Introduction
Discover how structured illumination microscopy works can help you see things in greater detail.

Immune Responses in Severe COVID-19 Patients
Speaker Professor Dexi Chen, the Director of the Beijing Institute of Hepatology, present data on immune responses in severe COVID-19.

Making the Perfect Blood Smear
Stop wasting time throwing out slide after slide trying to create a readable blood smear. Read our how-to guide for creating the perfect blood smear slide.

What Can Electron Microscopy Do for You?
The electron microscope (EM) – where electrons, rather than photons, make the image – fell out of fashion for a while, but it has come back refreshed. Modern electron microscopes cost less, use less electricity, and are generally easier to maintain than the older models, so it is likely that you can get your hands on one. Read on to learn more about this technique, and how to implement it into your research.

Pop Quiz!: Do You Know How a Coulter Counter Works?
Are you an immunologist or lab personnel dealing with counting tons of cells? Then you must have come across the elusive Coulter Counter! Read on to know a little history ofthe instrument’s technology and its working principle.

Feeder Cells – the What, Why and How
Feeder cells – your solution to difficult-to-grow cell problems. Find out what they are, why to use them, and how.

Markerless and Scarless Microbial Genome Engineering
Markerless and Scarless Microbial Genome Engineering On Demand Webinar Speaker Erik Eastlund Principal Scientist, Gene Editing and Novel Modalities, Merck KGaA, Darmstadt, Germany Erik is a principal scientist for Gene Editing and Novel Modalities at Merck KGaA, Darmstadt, Germany. His group is focused on developing microbial genome engineering tools while also engaging in a microbiome…
