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Search below to delve into the Bitesize Bio archive. Here, you’ll find over two decades of the best articles, live events, podcasts, and resources, created by real experts and passionate mentors, to help you improve as a bioscientist. Whether you’re looking to learn something new or dig deep into a topic, you’ll find trustworthy, human-crafted content that’s ready to inspire and guide you.
Why is SDS-PAGE run vertically? Agarose gel electrophoresis is run horizontally, so why not SDS-PAGE? Here are 3 great answers.
With the NanoDrop spectrophotometer, quantifying a DNA, RNA, or protein sample concentration is as easy. Here’s everything you need to know about the strengths and limitations of this handy spec.
Discover ways to perform total RNA extraction from TRIzol to kit-based and even old-school methods.
Circular dichroism is a type of spectroscopy that can tell you the type and percentage of secondary structure units in a protein sample. Here are 5 handy pointers on best circular dichroism practice to set up your experiment properly.
Getting science research grants is becoming increasingly competitive and difficult. Read our top tips to maximize your chances of success.
Circular dichroism is a type of spectroscopy that can tell you the type and percentage of secondary structure units in a protein sample. This article will take you through circular dichroism theory and some of its applications.
SDS-PAGE is the technique that unites life scientists. We all perform it during our research to separate protein analytes and, therefore, we all need a good SDS-PAGE gel recipe.
If you’ve worked in a lab, odds are you’ve had an encounter with filtration of one sort or another. Do you understand exactly how filters work, though? Or have you wondered why certain filters are used for certain lab applications?
Discover more about how ReadCube Papers can help you keep on top of your references.
Expressing your protein of interest but not sure if it’s properly folded or struggling with inclusion bodies? Read on to discover advice and tips for battling inclusion bodies and refolding proteins
There are several great protein staining methods, but how do you pick the one that’s appropriate to your intended application? Read on to find out.
Learn more about the key features of EndNote to work out if it’s the right reference manager for you.
Do you want to know about a cool way to detect and tell the difference between virus particles? Then read on to discover flow virometry!
Learn how Mendeley allows you to organize a library containing your favorite articles and generate citations and bibliographies while writing papers.
Discover more about biocuration, why it’s so important, and what it takes to become a biocurator. It turns out that biocuration as a career choice is easier than you might think!
This article reassesses the dangers of using ethidium bromide and compares some supposedly safer alternatives
Discover 6 critical scanning electron microscopy sample preparation points you need to know to get the best out of your SEM.
The interaction of proteins with ligands is an important phenomenon. Learn how to detect these interactions (and much more) using the thermal shift assay. In this article, we’ve got you covered with the basic theory and an easy protocol too.
Homology modeling is a powerful tool that enables you to predict protein structures. But how do you do it? Read on to find out.
Don’t just take it on faith that your measurements are accurate. Discover how to verify your measurements using gage R&R studies.
We’ll show you how to make a DIY stock of chemically competent E. coli, the workhorse in the molecular biology laboratory.
PubCrawler automatically searches PubMed and GenBank for queries that you specify, and emails you the results, helping you stay on top of your literature searches.
Laemmli buffer is used almost every day by life since researchers. But what do all those components actually do? Find out in this handy article
How do you make sure that the crystals you have grown are of your target protein? Can you tell salt and protein crystals apart without using X-ray diffraction? Yes, you can. Read on to discover five easy ways to distinguish between salt and protein crystals.
It’s all too easy to forget how many common lab chemicals are dangerous. Read on, as we bring you even more dangerous lab chemicals that you should not be messing with.
We’re all familiar with DNA and RNA. But have you heard of xeno nucleic acids (XNAs)? Read on to find out how they can be applied in biological research, and how you can start using them in your experiments.
Understanding how DNA extraction kits work is the key to troubleshooting your extraction issues.
Discover how you can visualize that notoriously difficult molecule, RNA using light-up RNA aptamers (LURAs).
With hazards all around, it’s easy to forget how deadly even common chemicals in the lab are. But don’t worry—we’ve compiled a list of common, dangerous chemicals to help you out.
This is the first installment in the DNA microarray series where I will introduce the technology and explain the basics.
Whether you’re simply seeking competent E. coli for a transformation experiment or building a panel intended for a whole project, it’s vital that you pick the right strain for your experiment. Find out more in our complete guide to choosing bacterial strains.
Are you struggling with your phenol-chloroform extraction or just looking to maximize the nucleic acid you retrieve? Then read our expert advice to improve your technique.
Phenol extraction is a common method for removing proteins from nucleic acids. Discover how phenol extraction of DNA works.
Ion-exchange chromatography is used to separate and purify proteins based on net charge at a particular pH. Here are the basics about this technique.
Do you need a way to estimate the molecular weight of a sample or protein? We walk you through one simple solution using a gel filtration chromatogram.
Making good quality electrocompetent E. coli is very easy. One morning’s work (with a bit of work ahead of time) is all it takes.
HEK293 cells are one of the most commonly used cell lines. But what are they? Why should you use them? And what does the ‘293’ mean?
Discover how the luciferase reporter assay works and how to get starting using it in your research.
Want to use Gateway cloning or having trouble using this technology? Find out how it works and get helpful tips to increase your success.
Need to brush up on your alternative splicing knowledge? We’re here to help with our guide to this splicing mechanism.
The eBook with top tips from our Researcher community.
