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Search below to delve into the Bitesize Bio archive. Here, you’ll find over two decades of the best articles, live events, podcasts, and resources, created by real experts and passionate mentors, to help you improve as a bioscientist. Whether you’re looking to learn something new or dig deep into a topic, you’ll find trustworthy, human-crafted content that’s ready to inspire and guide you.
There are a large number of microscope objective abbreviations relating to optical aberrations; here we’ll shed some light on some of the most common ones to get you up to speed in no time!
Are you finding the variety of available yeast media overwhelming? Read our guide to understand what’s in each and which is right for your fungus.
Do hemocytometers look scary and complicated with their multiple tiny squares, boxes, and grids? Take a look at our article and see how easy it actually is to use a hemocytometer.
Live imaging of phagocytosis helps capture the details of this dynamic process. Discover tips and tricks to visualizing this important cellular process.
Mass spectrometry can feel intimidating. Read this easy-to-follow guide to demystify mass spectrometry and learn how it can help your research.
Cryopreservation is crucial to the long-term maintenance of cells, so it’s important that you’re clued up on your freeze–thaw cycles. Check out our top tips for freezing and thawing cells.
Learn how the Point Spread Function affects what you see through your microscope and discover what you can do to improve your images.
Alkaline lysis for plasmid isolation? That’s like the ABCs in a molecular biology lab. Read this detailed article to understand the process behind this common technique.
If you need a multi-gene knockout or large-scale genomic modification, or want reduced off-target effects, then multiplex CRISPR is for you!
Discover what unnatural amino acids are, their applications, and how they can be used in your research in our beginner’s guide.
CRISPR interference allows for the regulation of gene expression in vivo. Here’s a short guide to how it works.
Live-cell imaging can bring a lot of clarity to cellular processes, but keeping your cells happy can be tricky. Read on to learn about 4 key parameters for achieving optimal conditions for live-cell imaging.
Read on to learn more about live cell imaging, including how high rate microscopy can help you capture rapid cellular processes.
If you need to copy, sequence, or quantify DNA, you need to know about PCR. Read our guide to the PCR process, and discover tips to help you avoid the most common PCR pitfalls.
qPCR primer design is a bit of science, a bit of magic, and a little bit of luck. Here’s the science to help you design the best primers for your experiments.
Why do you get three bands when running uncut plasmid DNA on agarose gels. Discover the answer and how it can help improve your DNA plasmid preps.
Want to know more about ethanol grades commonly used in the lab? We help you make sense of your flammables cabinet with our rundown of the ethanol grades typically used in molecular biology, as well as some important rules for how to use them correctly.
It’s not always easy deciding whether to run electrophoresis at a constant voltage, current, or power. Here, we outline the differences to help you make an informed decision.
Discover how chromatic and geometric imaging aberrations have been corrected over the last few centuries with the development of corrected lenses and objectives.
Are you struggling with your DNA clean-up? Then check out our top five methods so you can pick the best option for your experiments.
Discover the history of simple and compound microscopes in this first of our two-part series on the history of microscopes.
New to qPCR? Here’s a quick summary of one of the two most common analysis methods – double delta Ct analysis.
Are you having problems with tissue sectioning? Follow these 10 tissue sectioning tips to create the perfect tissue section every time without stressing out.
Want to know about stereo microscopes? This article answers what a stereo microscope is, how it works and why it’s a great tool for biologists!
Need a crash course in microbial identification methods? Here we give you a rundown of the methods available for the identification of bacteria, yeast, or filamentous fungi to the species level.
Getting publication perfect confocal images can be tricky. If you are struggling or just want to ensure you’re capturing the best images possible, check out our top 7 tips for confocal imaging.
Get the best out of your time on the microscope by understanding the refractive index of your experiment to optimize and increase your resolution.
If you’re thinking FRAP is short for frappuccino then you need to read this article. Discover the history, how it works, and why you’d want it in your confocal toolbox
Deciding on the right peptide sequence can make or break your experiment. Find out what to keep in mind when designing a synthetic peptide.
How does photoactivated localization microscopy (PALM) work? And what use can PALM microscopy be to you? This short introduction to PALM gives you the answers!
Good PALM sample preparation is the key to great images. Find out how to choose the right fluorescent proteins and learn some tips and tricks for sample prep.
Want to build your own microscope for almost nothing? You probably already have most of the tools that you need right in your lab or at home! Here’s how.
Check out our agarose gel hacks for troubleshooting your blurry or uneven bands, and tips for getting picture-perfect agarose gel images every time.
Can lasers be used to trap and move objects? Sure they can! Read on to know how you can use lasers in a cool technique called optical tweezers to manipulate minuscule objects under the microscope.
As is sadly the case in many experiments, site-directed mutagenesis (SDM) does not always work the way we would like it to the first time around. Here are a few tips to help you on your way when trying to troubleshoot a bothersome SDM reaction!
If you are interested in the sensory or motor function of your zebrafish model, this is the test to try.
Don’t get overexcited but we’ve got 7 top tips to help you minimize photodamage during your fluorescent live-cell imaging experiments.
Tips on staying sane from a student survivor of tedious lab tasks.
Don’t put all your eggs in one basket! Learn how to handle your eggs, prevent contamination and keep track of your experiments when performing the CAM assay.
A quick start guide to methods of assessing protein post-translational modifications
The eBook with top tips from our Researcher community.
