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Search below to delve into the Bitesize Bio archive. Here, you’ll find over two decades of the best articles, live events, podcasts, and resources, created by real experts and passionate mentors, to help you improve as a bioscientist. Whether you’re looking to learn something new or dig deep into a topic, you’ll find trustworthy, human-crafted content that’s ready to inspire and guide you.
Live-cell imaging can bring a lot of clarity to cellular processes, but keeping your cells happy can be tricky. Read on to learn about 4 key parameters for achieving optimal conditions for live-cell imaging.
Read on to learn more about live cell imaging, including how high rate microscopy can help you capture rapid cellular processes.
If you need to copy, sequence, or quantify DNA, you need to know about PCR. Read our guide to the PCR process, and discover tips to help you avoid the most common PCR pitfalls.
qPCR primer design is a bit of science, a bit of magic, and a little bit of luck. Here’s the science to help you design the best primers for your experiments.
Why do you get three bands when running uncut plasmid DNA on agarose gels. Discover the answer and how it can help improve your DNA plasmid preps.
Want to know more about ethanol grades commonly used in the lab? We help you make sense of your flammables cabinet with our rundown of the ethanol grades typically used in molecular biology, as well as some important rules for how to use them correctly.
It’s not always easy deciding whether to run electrophoresis at a constant voltage, current, or power. Here, we outline the differences to help you make an informed decision.
Discover how chromatic and geometric imaging aberrations have been corrected over the last few centuries with the development of corrected lenses and objectives.
Are you struggling with your DNA clean-up? Then check out our top five methods so you can pick the best option for your experiments.
Discover the history of simple and compound microscopes in this first of our two-part series on the history of microscopes.
New to qPCR? Here’s a quick summary of one of the two most common analysis methods – double delta Ct analysis.
Are you having problems with tissue sectioning? Follow these 10 tissue sectioning tips to create the perfect tissue section every time without stressing out.
Want to know about stereo microscopes? This article answers what a stereo microscope is, how it works and why it’s a great tool for biologists!
Need a crash course in microbial identification methods? Here we give you a rundown of the methods available for the identification of bacteria, yeast, or filamentous fungi to the species level.
Getting publication perfect confocal images can be tricky. If you are struggling or just want to ensure you’re capturing the best images possible, check out our top 7 tips for confocal imaging.
Get the best out of your time on the microscope by understanding the refractive index of your experiment to optimize and increase your resolution.
If you’re thinking FRAP is short for frappuccino then you need to read this article. Discover the history, how it works, and why you’d want it in your confocal toolbox
Deciding on the right peptide sequence can make or break your experiment. Find out what to keep in mind when designing a synthetic peptide.
How does photoactivated localization microscopy (PALM) work? And what use can PALM microscopy be to you? This short introduction to PALM gives you the answers!
Good PALM sample preparation is the key to great images. Find out how to choose the right fluorescent proteins and learn some tips and tricks for sample prep.
Want to build your own microscope for almost nothing? You probably already have most of the tools that you need right in your lab or at home! Here’s how.
Check out our agarose gel hacks for troubleshooting your blurry or uneven bands, and tips for getting picture-perfect agarose gel images every time.
Can lasers be used to trap and move objects? Sure they can! Read on to know how you can use lasers in a cool technique called optical tweezers to manipulate minuscule objects under the microscope.
As is sadly the case in many experiments, site-directed mutagenesis (SDM) does not always work the way we would like it to the first time around. Here are a few tips to help you on your way when trying to troubleshoot a bothersome SDM reaction!
If you are interested in the sensory or motor function of your zebrafish model, this is the test to try.
Don’t get overexcited but we’ve got 7 top tips to help you minimize photodamage during your fluorescent live-cell imaging experiments.
Tips on staying sane from a student survivor of tedious lab tasks.
Don’t put all your eggs in one basket! Learn how to handle your eggs, prevent contamination and keep track of your experiments when performing the CAM assay.
A quick start guide to methods of assessing protein post-translational modifications
A quick look at the first steps of metaphase spreads – the break down on breaking down your cells and the factors to keep in mind.
You might know the most common post-translational modifications, but there are many more than just phosphorylation and ubiquitination – come and test your knowledge!
Are you studying a small peptide or protein? Learn whether using synthetic peptides can save you hours of transfection, protein expression, and purification.
How good is your cell at recycling? In this guide, we explain what autophagic flux is, why you need to study it, and methods to get you started.
Are you studying angiogenesis? Is cell culture not cutting it but you’re not ready for an in vivo model? Check out the CAM assay.
Tips and tricks to get the most optimum and consistent results in a DSS-induced colitis model
Lysine acetylation isn’t just for histones. Read on to find out how to determine whether your favorite protein is lysine acetylated.
Using the right affinity tag can make protein purification a breeze. Read more to find out which tag is right for you.
Discover how to check DNA quality for long-read sequencing using electrophoresis and why pipetting carefully is so important.
Discover how structured illumination microscopy works can help you see things in greater detail.
Stop wasting time throwing out slide after slide trying to create a readable blood smear. Read our how-to guide for creating the perfect blood smear slide.
The eBook with top tips from our Researcher community.