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Do you know what that NA number is on your objective? We walk you through what the numerical aperture is and why it’s important.
There are a large number of microscope objective abbreviations relating to optical aberrations; here we’ll shed some light on some of the most common ones to get you up to speed in no time!
Are you finding the variety of available yeast media overwhelming? Read our guide to understand what’s in each and which is right for your fungus.
Do hemocytometers look scary and complicated with their multiple tiny squares, boxes, and grids? Take a look at our article and see how easy it actually is to use a hemocytometer.
Live imaging of phagocytosis helps capture the details of this dynamic process. Discover tips and tricks to visualizing this important cellular process.
Mass spectrometry can feel intimidating. Read this easy-to-follow guide to demystify mass spectrometry and learn how it can help your research.
Cryopreservation is crucial to the long-term maintenance of cells, so it’s important that you’re clued up on your freeze–thaw cycles. Check out our top tips for freezing and thawing cells.
Learn how the Point Spread Function affects what you see through your microscope and discover what you can do to improve your images.
Alkaline lysis for plasmid isolation? That’s like the ABCs in a molecular biology lab. Read this detailed article to understand the process behind this common technique.
If you need a multi-gene knockout or large-scale genomic modification, or want reduced off-target effects, then multiplex CRISPR is for you!
Discover what unnatural amino acids are, their applications, and how they can be used in your research in our beginner’s guide.
CRISPR interference allows for the regulation of gene expression in vivo. Here’s a short guide to how it works.
Using gloves in the lab is necessary for safety but can result in the dreaded “sweaty glove hands”. Read our top tips on how to banish those sweaty palms for good (or for at least as long as it takes to do your experiment)!
Live-cell imaging can bring a lot of clarity to cellular processes, but keeping your cells happy can be tricky. Read on to learn about 4 key parameters for achieving optimal conditions for live-cell imaging.
Read on to learn more about live cell imaging, including how high rate microscopy can help you capture rapid cellular processes.
If you need to copy, sequence, or quantify DNA, you need to know about PCR. Read our guide to the PCR process, and discover tips to help you avoid the most common PCR pitfalls.
Need a laugh? Check out our favorite Drosophila gene names.
Messing up the initial calculations in your experiment is setting yourself up for failure. Here is a quick refresh on calculating the number of molecules in any DNA sample.
qPCR primer design is a bit of science, a bit of magic, and a little bit of luck. Here’s the science to help you design the best primers for your experiments.
Why do you get three bands when running uncut plasmid DNA on agarose gels. Discover the answer and how it can help improve your DNA plasmid preps.
Want to know more about ethanol grades commonly used in the lab? We help you make sense of your flammables cabinet with our rundown of the ethanol grades typically used in molecular biology, as well as some important rules for how to use them correctly.
It’s not always easy deciding whether to run electrophoresis at a constant voltage, current, or power. Here, we outline the differences to help you make an informed decision.
Discover how chromatic and geometric imaging aberrations have been corrected over the last few centuries with the development of corrected lenses and objectives.
Are you struggling with your DNA clean-up? Then check out our top five methods so you can pick the best option for your experiments.
Discover the history of simple and compound microscopes in this first of our two-part series on the history of microscopes.
Pipetting errors getting you down? Learn how to avoid and correct errors that hurt your pipetting accuracy in this easy-to-follow article.
Are you getting the most out of your PubMed searches or are you wasting lots of time slogging through pages of results? We’ve compiled some top tips to help you refine your searches.
New to qPCR? Here’s a quick summary of one of the two most common analysis methods – double delta Ct analysis.
Are you having problems with tissue sectioning? Follow these 10 tissue sectioning tips to create the perfect tissue section every time without stressing out.
Interested in a career in bioinformatics? We’ve got the lowdown on the ways bioinformatics skills can be used, and the training you’ll need to pursue this career path.
Want to know about stereo microscopes? This article answers what a stereo microscope is, how it works and why it’s a great tool for biologists!
Need a crash course in microbial identification methods? Here we give you a rundown of the methods available for the identification of bacteria, yeast, or filamentous fungi to the species level.
A scientific research poster can be a great tool for drawing people into a conversation at a conference. We’ve pulled together our 10 top tips to help you prep perfect posters.
So you might be wondering why you bothered with all those years of failed experiments, committees, over-bearing supervisors, thesis writing, and thesis defending. Well, no matter where life takes you, you can now call yourself “Dr” whenever you want. And that can be more useful than you might think…
Performing successful experiments is a crucial skill for scientists. We’ve rounded up our top tips to help you achieve perfect procedures!
Getting publication perfect confocal images can be tricky. If you are struggling or just want to ensure you’re capturing the best images possible, check out our top 7 tips for confocal imaging.
Get the best out of your time on the microscope by understanding the refractive index of your experiment to optimize and increase your resolution.
If you’re thinking FRAP is short for frappuccino then you need to read this article. Discover the history, how it works, and why you’d want it in your confocal toolbox
Want to leave the lab but not sure what alternative career options are available? Our guide can help you decide what to do after hanging up your lab coat.
The prospect of writing an entire paper can be daunting. Our guide to planning a paper will help you break the project down into manageable steps.
The eBook with top tips from our Researcher community.