After writing my recent article on custom gene synthesis, I came across this article in the excellent Seven Stones systems biology blog that highlights the potential dark side of this emerging technology. The article describes a recent Nature Biotechnology commentary by B??gl et al 2007 in which executives from the DNA synthesis industry discuss regulation of their industry in order to address biosecurity concerns.
According to ArmsControlatWork.com, a leading gene synthesis company, Blue Heron Biotechnology, claim that they could synthesise something the size of the entire polio genome in around 12 weeks. Of course, companies like Blue Heron will, and in fact have (see the ArmsControlatWork article), turn(ed) down suspicious orders, but other companies may not be so conscientious.
From this, it’s easy to see how the decoupling of gene synthesis from any sort of template requirement could simplify life for wannabe bioterrorists, especially as the technology advances. Hopefully through the proposed framework and other similar initiatives, gene synthesis can be sufficiently regulated so that this fantastically useful technology does not switch the lights out for all of us.
Are you stuck in cloning hell?, Tired of doing ligations that don’t work? Want a faster, more efficient cloning procedure? You should try ligation independent cloning. A growing number of researchers swear by ligation independent cloning methods because they are simpler and more efficient than conventional cloning and as a recent convert to their ranks, […]
It’s great to have you in the Bitesize Bio family! We’ve sent you an email to confirm your registration. Please click on the link in the email or paste it into your browser to finalize your registration.
For more information on how to use Bitesize Bio, take a look at the following image (click it, for a larger version)
An error occured while registering you, please reload the page and try again