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Stop wasting time throwing out slide after slide trying to create a readable blood smear. Read our how-to guide for creating the perfect blood smear slide.
The electron microscope (EM) – where electrons, rather than photons, make the image – fell out of fashion for a while, but it has come back refreshed. Modern electron microscopes cost less, use less electricity, and are generally easier to maintain than the older models, so it is likely that you can get your hands on one. Read on to learn more about this technique, and how to implement it into your research.
Are you an immunologist or lab personnel dealing with counting tons of cells? Then you must have come across the elusive Coulter Counter! Read on to know a little history ofthe instrument’s technology and its working principle.
Feeder cells – your solution to difficult-to-grow cell problems. Find out what they are, why to use them, and how.
Working with mice doesn’t have to be intimidating. Read these tips to help keep your mouse-based experiments running smoothly.
Are you struggling to answer your research question using established models? Consider going rogue and switching to a non-model organism!
Same is dull and boring, right? Not when it comes to making media batches – learn how to be boring and get great results every time.
Yes, you can infect your eukaryotic cells with bacteria on purpose! Find out why and how in this article that lists steps for successful and productive infections.
Did you know that there are many alternatives to the animal-derived products we use in the lab? Read more for how and why you might want to make the switch.
Want to reduce the use of antibiotics in the lab? Start with switching to alternative cloning methods that use alternative selection pressures.
Shared microscopes have the potential to get dirty and spread nasties between samples and users. Check out our quick guide on how to clean and disinfect your microscope.
If you’re confused about what N numbers mean for cell lines, you’re not alone. We explain it all and give you a guide on best practice.
When microinjecting zebrafish, time is of the essence. Read these tips and tricks on how to prepare ahead of time and ensure a successful microinjection.
Discover how CRISPR can be scaled up for drug screening applications.
Are you frazzled? Constantly rushing from task to task? Stop and learn how cultivating awareness can make you calmer and happier in the lab.
This followup article on HPTLC gives a list of dos and don’ts while performing HPTLC to achieve precise and error-free results, and avoid false positives.
Are you mentoring an intern and nervous about how to be a good boss? This quirky and offbeat article has got some great tips!
Get robotic with HPTLC! This automated version of TLC can separate and quantify compounds – find out how!
Want to organize and tidy your lab? Read this detailed guide to a clutter-free and stress-free lab.
Want to increase siRNA stability and efficiency? Read on to learn five chemical modifications that will help.
There’s no need to shop till you drop. Our guide to where to get your next cell line from takes the stress out of cell line shopping.
Get your data out here! Learn about several venues that publish solid data, even if they don’t support your hypothesis or tell a story.
Find out how CRISPR-mediated gene activation (CRISPRa) and repression (CRISPRi) work and why you should consider using them in addition to your CRISPR knockouts.
Discover two CRISPR-based viral diagnostic strategies, DETECTR and SHERLOCK.
Fret no more over fuzzy bands! We uncover how gradient gels can give you better results, and maximize your precious samples when performing SDS-PAGE
Find out how modified variants of CRISPR nucleases provide gene editing with reduced off-target effects and can even control gene expression without altering the DNA sequence.
Discover how to validate your CRISPR gene editing, from the successful delivery of CRISPR reagents to the confirmation of desired genetic and phenotype changes.
Are you facing working from home? Find out how to prepare and stay productive.
Discover how to get started with CRISPR gene editing in your experiments with our key considerations.
DOIs got you confused? Find out what they are and how to use them.
3′ mRNA-seq is a NGS method to profile gene expression that is sensitive and straightforward but won’t blow your budget.
We are all familiar with bacterial cell lines as a means for protein expression and purification. But can you do the same with eukaryotic cell lines? Read on to learn some helpful tips and considerations when needing to get your hands on some eukaryotic protein.
While DNA and RNA extraction is a pretty common technique, it isn’t always the easiest. Read on to learn some top tips on how to successfully extract nucleic acids from even the toughest samples, like Arabidopsis seeds.
PubMed has had a makeover. Find out where your favorite features have moved to and what’s changed in this shiny new version.
Have you got a plasmid that others are begging to use? Perhaps your cell line is in high demand? We’ll show how using a repository can take the hassle out of sharing your reagents.
Mitochondrial DNA isolation can be time-consuming and laborious. Find out how to minimise the time needed for its extraction, while ensuring fantastic results.
There is an overwhelming selection of cell lines available, make sure you pick the right one for your work using our tips.
Working from home but don’t have a garage lab? We’ve got 10 ideas to keep you productive while you’re working away from the bench.
When it comes to profiling miRNAs there are lots of platforms available. We discuss the pros and cons of various miRNA profiling methods to help you choose the right one for your needs.
Are your cell membranes more of a hindrance than a help? Struggling to sneak your DNA inside? Why not break out and take your expression or metabolism studies cell-free. Find out the what, how and why of cell-free systems.
The eBook with top tips from our Researcher community.