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Selecting the right blood collection tubes for your experiment is crucial. But do you know what tubes to use for which type of blood sample? Read on to find the answers.
The emergence of Volume Electron Microscopy (vEM) has unlocked new possibilities in biological imaging, enabling us to visualize 3D structures of cells at high resolution. Learn more about this incredible technique in our latest article.
Discover what hematoxylin and eosin staining is used for and how it works, in this concise guide.
Purified proteins must be kept soluble and active. Discover how to design the perfect protein purification buffer—from additives you can include and their appropriate concentrations to important considerations.
Most experiments start with a piece of DNA—either plasmid DNA or genomic DNA. And your downstream uses for it dictate how much you need, what contaminants you can tolerate, and your extraction and purification methods. In this article, we explain the key differences between plasmid and genomic DNA extraction methods.
By removing the word ‘because’ from your vocabulary, you can gain a newfound sense of freedom, creativity, and authority in your decisions. Learn to make choices without justifications and experience the world with a fresh set of eyes.
Do you prepare samples for electron microscopy and want to save time, money, effort, and frustration? This article provides hands-on advice to help you get the best possible data out of your EM experiments.
Need to add extra nucleotides to your plasmid or other DNA sample? Here’s how to use overhang PCR to easily add extra bases using primers.
Investigating human diseases and genetic variation is complex, but CRISPR-edited induced pluripotent stem cells present a promising alternative to immortalized cell lines. This article delves into genome editing principles and offers practical steps for optimizing research techniques, ensuring more accurate and ethical studies.
We must preserve microorganisms for research continuity and to prevent frustrating delays. Here are several reliable ways to do it.
Learn about four fixatives for histology, which one you should pick, and how. Plus, get some top tips for perfect sample preservation.
So you’ve got your flow cytometry training booked and are one step closer to that precious data. Read our 7 top tips on how to get the most from your flow cytometry training.
Learn how confocal laser scanning microscopy works, its applications, and why it’s great for samples that are too thin to section.
We must lyse cells to extract our samples, but which cell lysis method is best for your cells? Read this article to learn about eight excellent methods.
Dive into the world of protein structure science, where AI is revolutionizing the field by offering accurate predictions and free, open-access tools. In this beginner’s guide, we’ll explore these groundbreaking tools, discuss their strengths and weaknesses, and examine the implications for traditional experimental methods like NMR and X-ray crystallography.
Here’s your reliable and adaptable nuclear extraction protocol. It contains buffer recipes, explanations of what the reagents do, and top tips to boost yields.
Genetic variants are critical to fields like evolution, diagnostics, and medicine—but they’re complex. This article breaks them down.
Maxam–Gilbert Sequencing. Slow and obsolete or niche but powerful? Discover how it works and learn about three modern applications.
Confused about yeast protein extraction methods? Let this article guide you through the process and help you select the most appropriate method based on your research goals and available resources.
Learn about what reagents are usable past their chemical expiry date, how can you check if they are still okay, and which ones you should throw out.
Want to boost your research through inspiration, creativity, fitness, and articulacy.?We’ve listed an assortment of fun hobbies for scientists.
Struggling with your cloning? It could be time to try blunt-end cloning. This easy introduction explains what it is, when to use it, and how.
Having problems with your in situ hybridization? We’ve got 7 simple tips to help you get outstanding results.
Not sure what water of crystallization is? This article explains everything you need to know so that you’re equipped with the knowledge to decide if it matters to your experiments.
Digital images are essential to communicate your data. Get the information and tools you need to take your scientific illustration to the next level!
Don’t let centrifugation scare you. Learn how to balance properly, when to use the brake, and what the difference is between RCF and RPM!
The phenomenon of measurement drift can occur and adversely affect analytical balances when weighing compounds. Read on for our guide on how to prevent this!
The more expensive your lab centrifuge, the more sensitive and the easier it is to break. What can we do to give these pricey monsters a long, successful tenure in the lab? Read our 5 easy tips.
What is protein crystallography? Whether you are about to enter the world of protein crystallography or work with a protein crystallographer on your grant, this article will be useful.
You know the drill. To prove your theory, you must show the colocalization of X and Y in a cell. Here are 2 ways to reveal protein colocalization.
Want to know how to use a fume hood? Keep your head out of it for starters. Here are 10 extra tips to keep you safe when using one!
We all have patterns for tasks. While good patterns are helpful, bad ones can sabotage your career. Learn to identify and destroy harmful patterns.
Discover how Ponceau S works, how to perform staining, and get a detailed guide to interpreting what the staining means when troubleshooting your failed blots.
Safety Data Sheets tell us how to handle and dispose of every chemical we use. This article explains what they are and how to decipher them.
It’s crucial that we stay safe in the lab. To prevent accidents, we should risk assess our work. So here’s how to conduct a risk assessment in 6 steps.
We all know acids are dangerous chemicals, and you should handle them carefully. But how should we handle bases? Read on for top tips for handling bases safely in the lab.
Whether you want to get started with fluorescence microscopy or already use it, this guide will ensure you know the basics and get the best out of your fluorescence microscopy.
Laboratories brim with nasty chemicals and bugs. PPE protects you from them, but only if you don’t commit any of these PPE sins!
Gloves protect your skin from the numerous hazards lurking in labs. To help you stay safe, we’ll review the many lab glove types, then give you some handy tips on double-gloving, working with liquid nitrogen, coping with latex allergies, and how to best follow glove etiquette.
To help you keep safe and sound, we’ll review the most common types of PPE for the face and eyes, and give you some pointers on when (and when not!) to use them.
The eBook with top tips from our Researcher community.