What is Water of Crystallization? Everything You Need to Know
Not sure what water of crystallization is? This article explains everything you need to know so that you’re equipped with the knowledge to decide if it matters to your experiments.
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Not sure what water of crystallization is? This article explains everything you need to know so that you’re equipped with the knowledge to decide if it matters to your experiments.
Digital images are essential to communicate your data. Get the information and tools you need to take your scientific illustration to the next level!
Don’t let centrifugation scare you. Learn how to balance properly, when to use the brake, and what the difference is between RCF and RPM!
The phenomenon of measurement drift can occur and adversely affect analytical balances when weighing compounds. Read on for our guide on how to prevent this!
The more expensive your lab centrifuge, the more sensitive and the easier it is to break. What can we do to give these pricey monsters a long, successful tenure in the lab? Read our 5 easy tips.
What is protein crystallography? Whether you are about to enter the world of protein crystallography or work with a protein crystallographer on your grant, this article will be useful.
You know the drill. To prove your theory, you must show the colocalization of X and Y in a cell. Here are 2 ways to reveal protein colocalization.
Want to know how to use a fume hood? Keep your head out of it for starters. Here are 10 extra tips to keep you safe when using one!
We all have patterns for tasks. While good patterns are helpful, bad ones can sabotage your career. Learn to identify and destroy harmful patterns.
Discover how Ponceau S works, how to perform staining, and get a detailed guide to interpreting what the staining means when troubleshooting your failed blots.
Safety Data Sheets tell us how to handle and dispose of every chemical we use. This article explains what they are and how to decipher them.
It’s crucial that we stay safe in the lab. To prevent accidents, we should risk assess our work. So here’s how to conduct a risk assessment in 6 steps.
We all know acids are dangerous chemicals, and you should handle them carefully. But how should we handle bases? Read on for top tips for handling bases safely in the lab.
Whether you want to get started with fluorescence microscopy or already use it, this guide will ensure you know the basics and get the best out of your fluorescence microscopy.
Laboratories brim with nasty chemicals and bugs. PPE protects you from them, but only if you don’t commit any of these PPE sins!
Gloves protect your skin from the numerous hazards lurking in labs. To help you stay safe, we’ll review the many lab glove types, then give you some handy tips on double-gloving, working with liquid nitrogen, coping with latex allergies, and how to best follow glove etiquette.
To help you keep safe and sound, we’ll review the most common types of PPE for the face and eyes, and give you some pointers on when (and when not!) to use them.
You can build your own PCR machine using tools and equipment you can get easily and without breaking the bank. Well, what are you waiting for?
ECL is an expensive reagent. Why not learn how to make ECL yourself? This cheap and simple option will give you better blots more often!
Learn the basics of how to passage cells in culture with this easy-to-follow guide. While the specifics change per cell line, the basics remain.
Biosafety cabinets keep your work safe from contamination, and you safe from your work. So here are 12 tips for Working in a biosafety cabinet!
Spectral unmixing in flow cytometry is the key to great data from your full spectrum flow cytometry. Get this wrong, and you risk unreliable results. Read our top 7 tips from a flow cytometry core facilities expert to nail your unmixing.
Do you know what each ingredient in cell culture media does? Read on to take a look at the common ingredients and break down their roles.
Not sure what we mean by cell passage number? Confused about how to calculate it? Wondering if there is a maximum number? We explain it all.
We often use size-exclusion chromatography to purify samples. Read this article to learn how to use it to measure sample molecular weight as well!
Need to get a handle on the fundamental differences between HPLC and GC to pick one for your studies? Here’s a quick explainer!
Want to use a cell line but not sure where to start? Or perhaps you’re just curious about the most commonly used cell lines. Our top 5 most commonly used cell lines will help you get a feel for the cells that many researchers turn to.
Do you fully understand why enzymes have the best catalytic activity within a specific temperature ranges? Find out in our handy guide.
While using serum in cell culture can keep your cells healthy and happy, there are some notable downsides. We discuss the pros and cons of using serum in cell culture media and how to remove it if you want to eliminate it from your workflow.
Do you need to learn about gas chromatography? This article takes you through the basic principles and instrumentation. With illustrations!
Not sure what FRET is, or just need a refresher on how FRET works? Read our short guide to understand the usefulness of FRET for studying protein-protein interactions.
Designing Cas13 gRNAs is a bit different from the standard Cas9. Read this guide to learn how it differs, and get a step-by-step guide on designing the perfect Cas13 gRNAs.
Discover what RNA quality control is, why it’s so important for your experiments, and how to undertake it with these 3 key considerations.
We show you how to read a scientific paper efficiently to make the most of your reading time.
Journal Club. So much more than reading a paper aloud. So many ways to mess it up. Got to present one? Then read our journal club toolkit.
Buffers provide a stable chemical environment for all our experiments. But how do buffers work? And how do you pick one? Read on to find out.
Getting involved in the post-publication review of scientific papers can seriously improve your critical analysis skills. Here’s how.
Working with chemicals is dangerous and can lead to injury, or worse. Follow these ten broadly applicable golden rules to help keep you and your colleagues working safely in the lab.
Here’s an easy guide on how to maintain your lab balance. Following these tips will ensure your balance remains clean and perhaps most importantly, accurate.
You may be familiar with standard single fragment ligations, but did you know you can ligate multiple fragments into your vector all at the same time! Discover how to perform multiple fragment ligation, including the different methods and troubleshooting tips for when things go wrong.

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