How FRET Works: A Guide to Visualizing Protein Interactions
Not sure what FRET is, or just need a refresher on how FRET works? Read our short guide to understand the usefulness of FRET for studying protein-protein interactions.
Read MoreA Step-by-step Guide to Designing Cas13 gRNAs
Designing Cas13 gRNAs is a bit different from the standard Cas9. Read this guide to learn how it differs, and get a step-by-step guide on designing the perfect Cas13 gRNAs.
Read MoreHow to Perform RNA Quality Control in the Lab: 3 Key Considerations
Discover what RNA quality control is, why it’s so important for your experiments, and how to undertake it with these 3 key considerations.
Read MoreStand up for Science: How to Detect and Fight Misinformation
Misinformation is a common problem across the internet and particularly on social media. Learn how to identify misinformation in science and what to do when you see it being spread.
Read MoreHow to Read a Scientific Paper
We show you how to read a scientific paper efficiently to make the most of your reading time.
Read MoreJournal Club: How to Prepare Effectively and Smash Your Presentation
Journal Club. So much more than reading a paper aloud. So many ways to mess it up. Got to present one? Then read our journal club toolkit.
Read MoreHow Do Buffers Work?
Buffers provide a stable chemical environment for all our experiments. But how do buffers work? And how do you pick one? Read on to find out.
Read MorePre- and Post-Publication Peer Review and Why You Should Get Involved
Getting involved in the post-publication review of scientific papers can seriously improve your critical analysis skills. Here’s how.
Read More10 Golden Rules to Working Safely in the Lab: What Chemists Wish Biologists Knew
Working with chemicals is dangerous and can lead to injury, or worse. Follow these ten broadly applicable golden rules to help keep you and your colleagues working safely in the lab.
Read MoreHow to Clean and Calibrate Your Lab Balance
Here’s an easy guide on how to maintain your lab balance. Following these tips will ensure your balance remains clean and perhaps most importantly, accurate.
Read MoreHow Chromatography Works: Separation Science Explained with 5 Simple Examples
In biosciences, we purify our target molecules using chromatography. So, we need a thorough understanding of how chromatography works!
Read MoreMultiple Fragment Ligation: The Why and How
You may be familiar with standard single fragment ligations, but did you know you can ligate multiple fragments into your vector all at the same time! Discover how to perform multiple fragment ligation, including the different methods and troubleshooting tips for when things go wrong.
Read MoreTake Care of Your Tools: Cleaning Pipettes
Contamination in your pipette can mean contamination in your experiments, making cleaning pipettes regularly critical. Here’s an easy guide on how to do it.
Read MoreMethods for Relative Quantification of qPCR Data: Yes, There is More Than One
Want to know the best way to perform relative quantification for your qPCR data? Read on.
Read MoreKit-Free DNA Gel Extraction Methods: 3 Old School Protocols to Save Money
Kits for DNA gel extraction are a great way to save time in the lab, but they are costly and produce much plastic waste. Discover three easy kit-free DNA gel extraction methods that can save you money and reduce waste in the lab.
Read MoreThe 4 Important Steps for Western Blot Quantification
Western blot quantification can show how protein expression changes between conditions and treatments. Discover the 4 critical steps you need for quantification.
Read MoreWhat is Touchdown PCR? A Primer and 5 Easy Tips For Success
Got non-specific PCR amplification? You need touchdown PCR! Discover what it is, how it works, and get 5 top tips for performing touchdown PCR.
Read MoreAccessibility in Science: How Can We Make Science More Accessible?
Let’s be honest—we scientists don’t always present our science in ways that are accessible to everyone. Nor is lab-based science always accessible. Explore what accessibility in science is and how we can all make science more accessible and inclusive.
Read MoreHow to Use a pH Meter Correctly in 4 Simple Steps
A neglected pH meter means less reliable experiments, poor reproducibility, and your time wasted. So, learn how to use a pH meter correctly!
Read MoreHow to Handle Strong Acids in the Lab
Acids are common and essential chemicals in any research laboratory. In this article, you’ll get advice on how to handle strong acids safely to give you the confidence to routinely prepare, handle, and dispose of them in the lab.
Read MoreHow to Check the Accuracy of Your Pipette in 7 Easy Steps
I’d bet that your trusty pipette is probably one the the most often used tools in the lab. But do you have any idea how to check the accuracy of your pipette? We’ll take you though how to do this in just 7 easy steps.
Read More5 Ways to Destroy your Agarose Gel and How to Avoid Them!
Pouring and running an agarose gel should be a simple and routine procedure, but there are a surprising number of ways to destroy your agarose gel.
Read MoreCRISPR-Cas13: How to Revolutionize Your RNA Research
CRISPR isn’t just about DNA editing. Discover how you can use Cas13 proteins in your research to knock down, modify or track RNAs in mammalian cells.
Read MoreTop 5 Protein Quantification Assays
When working with proteins, accurate protein quantification is key for getting reliable data. Here are the top 5 quantification assays.
Read MoreProblems Amplifying GC-rich regions? 5 Easy Solutions
Are you having problems amplifying GC-rich regions in your PCR reactions? Read this article for 5 easy tips to address these issues!
Read MoreThe qPCR Standard Curve: The Key to Good qPCR Data
Can’t be bothered doing a qPCR standard curve? Find out why it’s important to getting great results and how to do it.
Read MoreHow Using Oil Immersion Microscopy Can Increase Your Resolution
Oil immersion microscopy can improve your resolution in microscopy. This article will explain why this is the case and how you can use oil immersion microscopy in the lab!
Read MoreApplications of Artificial Intelligence in Biology: An Easy Intro to AI for Researchers
Get a short introduction to AI including key terminology, example applications of artificial intelligence in biology, and resources to help you get started.
Read MoreThe Basics of NMR Part 3: Multidimensional NMR
NMR is a powerful structural tool for studying proteins. Learn how to use multidimensional NMR to identify ligand binding sites and more!
Read MoreThe Top 10 Worst Lab Smells
Working in a lab can be a smelly business. Let’s countdown some of the worst lab smells! Then, you can suggest your own.
Read MoreHow (and Why) To Manipulate Plasmid Copy Number
Here we take a closer look at plasmid copy number and examine how it can be manipulated in the lab giving you flexibility in your work.
Read MoreHow Confluent Are Your Cells? A Beginner’s Guide to Measuring Cell Culture Confluency
Cell confluency can affect cell behavior and growth. Find out what confluency is, how to measure it, and why it is a crucial consideration for your experiments.
Read MoreThe Basics of NMR Part 2: NMR and Protein Dimerization
NMR can generate tons of useful data for protein samples. Learn all about NMR and Protein Dimerization in this easy intro.
Read MoreCreativity in Science: How a Good Imagination Can Help Your Research
It pays dividends to think creatively about your research. Here are 8 tips to supercharge creativity in science and ensure a great environment to help your imagination flourish.
Read MoreDNA Ligation: How it Works & 6 Top Tips
Understanding the basic (and simple!) chemistry behind DNA ligation will help you get better DNA ligation results. Learn all about it here.
Read MoreThe Basics of NMR Part 1: Assessing Protein Folding by NMR
NMR is a structural tool that plays second fiddle to crystallography. But there’s a cheap, label-free method of investigating protein folding by NMR.
Read More3 Easy Ways to Mimic Phosphorylation
Discover what phosphorylation is, understand why you might want to mimic it, and learn 3 ways to mimic phosphorylation for both in vitro and in vivo applications
Read MoreSimplicity in Science: How to Increase your Research Effectiveness by Doing Less
Discover how embracing simplicity in science can make you a more effective researcher while reducing your workload.
Read MoreTips on Receiving and Applying Constructive Feedback for Scientists
Are you looking to improve your lab work, publication record, and grant success rate? Then read our guide to feedback—what it is, where it should come from, and how to give it to others.
Read MoreWhat Is Cryo-Electron Microscopy? A Brief Introduction
You don’t have to be a genius to understand Cryo-EM. Discover the fundamentals of this powerful microscopy tool and what propelled it into the scientific mainstream.
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