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Meltdown: A Hot Introduction to the Thermal Shift Assay

The interaction of proteins with ligands is an important phenomenon. Learn how to detect these interactions (and much more) using the thermal shift assay. In this article, we’ve got you covered with the basic theory and an easy protocol too.

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5 Easy Ways to Tell Salt and Protein Crystals Apart

How do you make sure that the crystals you have grown are of your target protein? Can you tell salt and protein crystals apart without using X-ray diffraction? Yes, you can. Read on to discover five easy ways to distinguish between salt and protein crystals.

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Choosing the Right Bacterial Strains for Your Lab

Whether you’re simply seeking competent E. coli for a transformation experiment or building a panel intended for a whole project, it’s vital that you pick the right strain for your experiment. Find out more in our complete guide to choosing bacterial strains.

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DIY Electrocompetent E. coli

Making good quality electrocompetent E. coli is very easy. One morning’s work (with a bit of work ahead of time) is all it takes.

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What the HEK? A Beginner’s Guide to HEK293 Cells 

If you’re at all familiar with cell culture, you’ve probably heard of HEK293 cells. HEK293 cells are one of the most commonly used cell lines in laboratories across the globe. But what are they? Why should you use them? And what does the ‘293’ mean? Are HEK293T cells the same thing? Read on for answers…

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