An introduction to Photoactivated Localization Microscopy (PALM)
How does photoactivated localization microscopy (PALM) work? And what use can PALM microscopy be to you? This short introduction to PALM gives you the answers!
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How does photoactivated localization microscopy (PALM) work? And what use can PALM microscopy be to you? This short introduction to PALM gives you the answers!
Good PALM sample preparation is the key to great images. Find out how to choose the right fluorescent proteins and learn some tips and tricks for sample prep.
Want to build your own microscope for almost nothing? You probably already have most of the tools that you need right in your lab or at home! Here’s how.
Rounding off our series of tips for writing your thesis in Microsoft Word, the final post covers page numbering, shortcut tips, and cover pages.
The end is in sight! You’ve drafted your individual thesis chapters and now it’s time to combine them into a single thesis master document. Follow our easy step-by-step instructions to get your thesis submission-ready.
Check out our agarose gel hacks for troubleshooting your blurry or uneven bands, and tips for getting picture-perfect agarose gel images every time.
Can lasers be used to trap and move objects? Sure they can! Read on to know how you can use lasers in a cool technique called optical tweezers to manipulate minuscule objects under the microscope.
Our latest tips for thesis writing with Word highlight three useful tools that can help you effortlessly create an easily navigatable thesis using built-in Word tools.
As is sadly the case in many experiments, site-directed mutagenesis (SDM) does not always work the way we would like it to the first time around. Here are a few tips to help you on your way when trying to troubleshoot a bothersome SDM reaction!
Get your thesis writing off to a great start by learning how to create a thesis outline in Microsoft Word.
If you are interested in the sensory or motor function of your zebrafish model, this is the test to try.
Don’t get overexcited but we’ve got 7 top tips to help you minimize photodamage during your fluorescent live-cell imaging experiments.
Tips on staying sane from a student survivor of tedious lab tasks.
Don’t put all your eggs in one basket! Learn how to handle your eggs, prevent contamination and keep track of your experiments when performing the CAM assay.
A quick start guide to methods of assessing protein post-translational modifications
Sharing research articles legally isn’t always straightforward, even when you are the author. Find out why sharing your article could put you in a sticky situation and learn how to avoid it!
A quick look at the first steps of metaphase spreads – the break down on breaking down your cells and the factors to keep in mind.
You might know the most common post-translational modifications, but there are many more than just phosphorylation and ubiquitination – come and test your knowledge!
Are you studying a small peptide or protein? Learn whether using synthetic peptides can save you hours of transfection, protein expression, and purification.
How good is your cell at recycling? In this guide, we explain what autophagic flux is, why you need to study it, and methods to get you started.
If choosing between a PhD or a Master’s has you frazzled, don’t panic. We weigh the pros and cons of both in terms of time, money, and career prospects.
Is patching clamping a problem? Struggling to get a good seal? There is no need to stress! We’ve got tips on picking and preparing the perfect pipette for your patch clamping experiment!
Researchers need to access journal articles, but paywalls can sometimes put up a fight. Discover the different legal ways you can access paywalled articles.
Thesis defenses are supposed to be grueling, horrific affairs that you fear for weeks beforehand, right? What if there was a way to get through your thesis without tears, torture, and perhaps even enjoy it?
Are you studying angiogenesis? Is cell culture not cutting it but you’re not ready for an in vivo model? Check out the CAM assay.
Have you ever given thought to how you are disposing of antibiotics in the lab and whether or not it’s correct? Discover the problems associated with improper antibiotic disposal and how to correctly dispose of different antibiotics in the lab.
Tips and tricks to get the most optimum and consistent results in a DSS-induced colitis model
Lysine acetylation isn’t just for histones. Read on to find out how to determine whether your favorite protein is lysine acetylated.
Using the right affinity tag can make protein purification a breeze. Read more to find out which tag is right for you.
Discover how to check DNA quality for long-read sequencing using electrophoresis and why pipetting carefully is so important.
Discover how structured illumination microscopy works can help you see things in greater detail.
Automate almost everything by learning Python. Discover why Python is a useful language for Biologists and discover how you can teach yourself!
Are needing to choose a microglial cell line? Want to ensure you are currently using the right one for your needs? Discover the different options available and how to choose.
Working away from the bench doesn’t mean your research has to suffer. Read more on how to take advantage of time away from the lab so you can return better than ever.
Don’t be fooled by bad data. Make sure your results are reliable with this quick guide to determining LOQ and LOD in Excel.
How can you tackle work when it seems daunting or even impossible to know what will happen and when? Take things one bite at a time and try time blocking!
Ever wonder why almost everyone uses FBS in cell-culture media? Read more on how FBS became such a powerhouse and see what the future may have in store for this ubiquitous reagent.
Stop wasting time throwing out slide after slide trying to create a readable blood smear. Read our how-to guide for creating the perfect blood smear slide.
The electron microscope (EM) – where electrons, rather than photons, make the image – fell out of fashion for a while, but it has come back refreshed. Modern electron microscopes cost less, use less electricity, and are generally easier to maintain than the older models, so it is likely that you can get your hands on one. Read on to learn more about this technique, and how to implement it into your research.
Are you an immunologist or lab personnel dealing with counting tons of cells? Then you must have come across the elusive Coulter Counter! Read on to know a little history ofthe instrument’s technology and its working principle.
Enhance accuracy, reproducibility, and insight in 2D cell culture research.

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