What Is Protein Crystallography? Structure Solution Explained
What is protein crystallography? Whether you are about to enter the world of protein crystallography or work with a protein crystallographer on your grant, this article will be useful.
Read MoreProtein Colocalization: 2 Essential Methods to Prove Protein Overlap
You know the drill. To prove your theory, you must show the colocalization of X and Y in a cell. Here are 2 ways to reveal protein colocalization.
Read MoreHow to Use a Fume Hood: 10 Top Tips
Want to know how to use a fume hood? Keep your head out of it for starters. Here are 10 extra tips to keep you safe when using one!
Read MoreAre Your Patterns Holding Your Research Back?
We all have patterns for tasks. While good patterns are helpful, bad ones can sabotage your career. Learn to identify and destroy harmful patterns.
Read MoreWhat Ponceau S Staining Can Reveal About Your Western Blot
Discover how Ponceau S works, how to perform staining, and get a detailed guide to interpreting what the staining means when troubleshooting your failed blots.
Read MoreDeciphering your Materials Safety Data Sheet
Safety Data Sheets tell us how to handle and dispose of every chemical we use. This article explains what they are and how to decipher them.
Read MoreLiquid Nitrogen Safety In The Lab: 10 Tips To Avoid LN2 Dangers
Liquid nitrogen isn’t just cool, it’s potentially deadly. We share our 10 tips for staying safe while working with liquid nitrogen.
Read MoreHow to Conduct a Risk Assessment: 6 Essential Steps to a Safer Lab
It’s crucial that we stay safe in the lab. To prevent accidents, we should risk assess our work. So here’s how to conduct a risk assessment in 6 steps.
Read MoreHow to Handle Bases in the Lab: Everything You Need to Know
We all know acids are dangerous chemicals, and you should handle them carefully. But how should we handle bases? Read on for top tips for handling bases safely in the lab.
Read MoreFluorescence Microscopy: From Principles to Applications
Whether you want to get started with fluorescence microscopy or already use it, this guide will ensure you know the basics and get the best out of your fluorescence microscopy.
Read More10 Common PPE Sins
Laboratories brim with nasty chemicals and bugs. PPE protects you from them, but only if you don’t commit any of these PPE sins!
Read MoreGuard Yourself with Our Great Lab Glove Selection Guide
Gloves protect your skin from the numerous hazards lurking in labs. To help you stay safe, we’ll review the many lab glove types, then give you some handy tips on double-gloving, working with liquid nitrogen, coping with latex allergies, and how to best follow glove etiquette.
Read MorePPE for Eye and Face Protection—Better Safe than Sorry!
To help you keep safe and sound, we’ll review the most common types of PPE for the face and eyes, and give you some pointers on when (and when not!) to use them.
Read MoreHow to Build Your Own PCR Machine
You can build your own PCR machine using tools and equipment you can get easily and without breaking the bank. Well, what are you waiting for?
Read MoreHow To Make ECL Reagent: 4 Ingredients, Better Blots
ECL is an expensive reagent. Why not learn how to make ECL yourself? This cheap and simple option will give you better blots more often!
Read MoreHow To Passage Cells in Culture
Learn the basics of how to passage cells in culture with this easy-to-follow guide. While the specifics change per cell line, the basics remain.
Read More12 Top Tips for Working in a Biosafety Cabinet
Biosafety cabinets keep your work safe from contamination, and you safe from your work. So here are 12 tips for Working in a biosafety cabinet!
Read MoreNail Your Unmixing for Full Spectrum Flow Cytometry: 7 Top Tips
Spectral unmixing in flow cytometry is the key to great data from your full spectrum flow cytometry. Get this wrong, and you risk unreliable results. Read our top 7 tips from a flow cytometry core facilities expert to nail your unmixing.
Read MoreWhat’s in Your Cell Culture Medium?
Do you know what each ingredient in cell culture media does? Read on to take a look at the common ingredients and break down their roles.
Read More3 Hot Tips to Optimize Your Western Blot Transfers
Are you struggling with ugly and unreadable western blots? Here are 3 ways to optimize your western blot transfer and get blots to be proud of.
Read MoreUnderstanding Cell Passage Number and How to Calculate it for Cell Cultures
Not sure what we mean by cell passage number? Confused about how to calculate it? Wondering if there is a maximum number? We explain it all.
Read MoreHow to Measure Molecular Weight Using Size-Exclusion Chromatography (SEC)
We often use size-exclusion chromatography to purify samples. Read this article to learn how to use it to measure sample molecular weight as well!
Read MoreHPLC and GC: 6 Fundamental Differences Made Simple to Enhance Your Research
Need to get a handle on the fundamental differences between HPLC and GC to pick one for your studies? Here’s a quick explainer!
Read MoreTop 5 of the Most Commonly Used Cell Lines
Want to use a cell line but not sure where to start? Or perhaps you’re just curious about the most commonly used cell lines. Our top 5 most commonly used cell lines will help you get a feel for the cells that many researchers turn to.
Read MoreUnderstanding The Optimum Temperature For Enzymes
Do you fully understand why enzymes have the best catalytic activity within a specific temperature ranges? Find out in our handy guide.
Read MoreGoing Serum-Free: The How and Why of Removing Serum From Your Media
While using serum in cell culture can keep your cells healthy and happy, there are some notable downsides. We discuss the pros and cons of using serum in cell culture media and how to remove it if you want to eliminate it from your workflow.
Read MoreGas Chromatography: What It Is, How It Works, and 5 Critical Components
Do you need to learn about gas chromatography? This article takes you through the basic principles and instrumentation. With illustrations!
Read MoreHow FRET Works: A Guide to Visualizing Protein Interactions
Not sure what FRET is, or just need a refresher on how FRET works? Read our short guide to understand the usefulness of FRET for studying protein-protein interactions.
Read MoreA Step-by-step Guide to Designing Cas13 gRNAs
Designing Cas13 gRNAs is a bit different from the standard Cas9. Read this guide to learn how it differs, and get a step-by-step guide on designing the perfect Cas13 gRNAs.
Read MoreHow to Perform RNA Quality Control in the Lab: 3 Key Considerations
Discover what RNA quality control is, why it’s so important for your experiments, and how to undertake it with these 3 key considerations.
Read MoreStand up for Science: How to Detect and Fight Misinformation
Misinformation is a common problem across the internet and particularly on social media. Learn how to identify misinformation in science and what to do when you see it being spread.
Read MoreHow to Read a Scientific Paper
We show you how to read a scientific paper efficiently to make the most of your reading time.
Read MoreJournal Club: How to Prepare Effectively and Smash Your Presentation
Journal Club. So much more than reading a paper aloud. So many ways to mess it up. Got to present one? Then read our journal club toolkit.
Read MoreHow Do Buffers Work?
Buffers provide a stable chemical environment for all our experiments. But how do buffers work? And how do you pick one? Read on to find out.
Read MorePre- and Post-Publication Peer Review and Why You Should Get Involved
Getting involved in the post-publication review of scientific papers can seriously improve your critical analysis skills. Here’s how.
Read More10 Golden Rules to Working Safely in the Lab: What Chemists Wish Biologists Knew
Working with chemicals is dangerous and can lead to injury, or worse. Follow these ten broadly applicable golden rules to help keep you and your colleagues working safely in the lab.
Read MoreHow to Clean and Calibrate Your Lab Balance
Here’s an easy guide on how to maintain your lab balance. Following these tips will ensure your balance remains clean and perhaps most importantly, accurate.
Read MoreHow Chromatography Works: Separation Science Explained with 5 Simple Examples
In biosciences, we purify our target molecules using chromatography. So, we need a thorough understanding of how chromatography works!
Read MoreMultiple Fragment Ligation: The Why and How
You may be familiar with standard single fragment ligations, but did you know you can ligate multiple fragments into your vector all at the same time! Discover how to perform multiple fragment ligation, including the different methods and troubleshooting tips for when things go wrong.
Read MoreTake Care of Your Tools: Cleaning Pipettes
Contamination in your pipette can mean contamination in your experiments, making cleaning pipettes regularly critical. Here’s an easy guide on how to do it.
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