The Basics of NMR Part 2: NMR and Protein Dimerization
NMR can generate tons of useful data for protein samples. Learn all about NMR and Protein Dimerization in this easy intro.
Read MoreCreativity in Science: How a Good Imagination Can Help Your Research
It pays dividends to think creatively about your research. Here are 8 tips to supercharge creativity in science and ensure a great environment to help your imagination flourish.
Read MoreDNA Ligation: How it Works & 6 Top Tips
Understanding the basic (and simple!) chemistry behind DNA ligation will help you get better DNA ligation results. Learn all about it here.
Read MoreThe Basics of NMR Part 1: Assessing Protein Folding by NMR
NMR is a structural tool that plays second fiddle to crystallography. But there’s a cheap, label-free method of investigating protein folding by NMR.
Read More3 Easy Ways to Mimic Phosphorylation
Discover what phosphorylation is, understand why you might want to mimic it, and learn 3 ways to mimic phosphorylation for both in vitro and in vivo applications
Read MoreSimplicity in Science: How to Increase your Research Effectiveness by Doing Less
Discover how embracing simplicity in science can make you a more effective researcher while reducing your workload.
Read MoreTips on Receiving and Applying Constructive Feedback for Scientists
Are you looking to improve your lab work, publication record, and grant success rate? Then read our guide to feedback—what it is, where it should come from, and how to give it to others.
Read MoreWhat Is Cryo-Electron Microscopy? A Brief Introduction
You don’t have to be a genius to understand Cryo-EM. Discover the fundamentals of this powerful microscopy tool and what propelled it into the scientific mainstream.
Read MoreA Short History of Cryo-Electron Microscopy
The slow, inching progress of cryo-EM towards the scientific mainstream can be told as a story with three parts. So take a step back and enjoy a short history of cryo-electron microscopy.
Read MoreHow UV Light Damages DNA and the Havoc it Can Cause to Your Experiments
Learn how UV radiation causes DNA mutations and discover more about the mechanisms underlying skin cancer, as well as the detrimental effects that UV light can have on our DNA-based experiments.
Read MoreCryo-EM Sample Prep: 5 Crucial Considerations
You don’t have to be a brainbox to get your samples ready for cryo-EM, but a little wisdom goes a long way. Learn how to tend to your tissues, organize your organelles, and prepare your proteins to get the micrographs you’ve always dreamed of.
Read MoreThe 2 Main Electron Microscopy Techniques: SEM vs TEM
Microscopy is a huge and active field. Sometimes, it’s easy to forget the basics. Read our biologists’ guide to electron microscopy techniques.
Read MoreSustainable Research: 12 Simple Hacks to Reduce the Environmental Impact of Your Research
It’s a tough reality, but research can be damaging to the environment. Discover our simple tips and do more sustainable research.
Read MoreApplications of Electron Microscopy: An Easy Intro for Biologists
Microscopy is a huge and active field. Sometimes, it’s easy to forget the basics. Read our biologists’ intro to applications of electron microscopy.
Read More11 qPCR Papers Every Researcher Should Know
Whether you’re generating, analyzing, or reviewing qPCR data you need to understand how it works and best practices. That’s why we’ve pulled together our top qPCR papers every researcher should read.
Read MoreBetter Plasmid Purification: 11 Reasons Your Plasmid Yield is Low
Are your plasmid preps giving your poor yields? We’ve got 11 reasons that might be causing it and how to fix them.
Read MoreZotero Reference Manager: A Super Simple Guide for Busy Researchers
Organizing your files is simple with Zotero; we’ve got the lowdown on functionality, usability, and access.
Read MoreThe Importance of Delegation for Scientists
The art of delegation can help save time and give you a happy, more productive lab life. Discover how with our easy guide to delegation for scientists.
Read MoreThe Definitive Guide to pH, pKa, and pI
We all rely on pH, pKa, and pI for a vast amount of our research. But what is pH? How does it relate to pKa and pI? Read the definitive guide.
Read MoreProtein Structure Analysis: Extra Information in a Protein Data Bank File
Getting to know your protein’s structure can help uncover deeper insights and inspire new hypotheses. Discover how protein data bank files can help.
Read MoreHow Does Peer Review in Science Work?
If you’re unsure as to how the peer-review process works, the difference between open and double-blind peer review or are wondering if peer review is broken, read on.
Read MoreWhy Is SDS-PAGE Run Vertically? Here are 3 Great Answers
Why is SDS-PAGE run vertically? Agarose gel electrophoresis is run horizontally, so why not SDS-PAGE? Here are 3 great answers.
Read MoreStrengths and Limitations of the Amazing NanoDrop™ Spectrophotometer
With the NanoDrop spectrophotometer, quantifying a DNA, RNA, or protein sample concentration is as easy. Here’s everything you need to know about the strengths and limitations of this handy spec.
Read MoreTotal RNA Extraction: Easy Methods for Getting High-Purity RNA
Discover ways to perform total RNA extraction from TRIzol to kit-based and even old-school methods.
Read MoreAn Introduction to Circular Dichroism Part 2: Circular Dichroism Practice
Circular dichroism is a type of spectroscopy that can tell you the type and percentage of secondary structure units in a protein sample. Here are 5 handy pointers on best circular dichroism practice to set up your experiment properly.
Read MoreTop Tips for Getting Science Research Grants
Getting science research grants is becoming increasingly competitive and difficult. Read our top tips to maximize your chances of success.
Read MoreHow to Clean up Chemical Spills in the Lab: 4 Essential Rules
No matter how small or large, chemical spills require immediate attention. Learn how to manage spills by following these 4 essential rules.
Read MoreAn Introduction to Circular Dichroism Part 1: Circular Dichroism Theory
Circular dichroism is a type of spectroscopy that can tell you the type and percentage of secondary structure units in a protein sample. This article will take you through circular dichroism theory and some of its applications.
Read MoreA Simple SDS-PAGE Gel Recipe and 10-Step Casting Protocol for Perfect Gels
SDS-PAGE is the technique that unites life scientists. We all perform it during our research to separate protein analytes and, therefore, we all need a good SDS-PAGE gel recipe.
Read More5 Protein Crystallization Seeding Techniques for Bigger and Better Crystals
Protein crystals are crucial for structure solution via X-ray crystallography but are notoriously hard to grow. We’ve got you covered with 5 clever protein crystallization seeding methods to grow impressive protein crystals.
Read MoreHow Filtration Works: A Short Guide for Biologists
If you’ve worked in a lab, odds are you’ve had an encounter with filtration of one sort or another. Do you understand exactly how filters work, though? Or have you wondered why certain filters are used for certain lab applications?
Read MoreHow To Get Organized With Reference Managers for Science—ReadCube Papers
Discover more about how ReadCube Papers can help you keep on top of your references.
Read MoreA Protein Renaturation Toolkit: 21 Tips and Tricks for Refolding Proteins
Expressing your protein of interest but not sure if it’s properly folded or struggling with inclusion bodies? Read on to discover advice and tips for battling inclusion bodies and refolding proteins
Read MoreProtein Staining Methods: An Overview of 3 of the Best
There are several great protein staining methods, but how do you pick the one that’s appropriate to your intended application? Read on to find out.
Read MoreHow to Get Organized With Reference Managers for Science—EndNote
Learn more about the key features of EndNote to work out if it’s the right reference manager for you.
Read MoreFlow Cytometry Gone Viral: Introducing Flow Virometry
Do you want to know about a cool way to detect and tell the difference between virus particles? Then read on to discover flow virometry!
Read MoreHow To Get Organized With Reference Managers for Science—Mendeley
Learn how Mendeley allows you to organize a library containing your favorite articles and generate citations and bibliographies while writing papers.
Read MoreTop 10 Best Science Podcasts For Researchers
Facing hours of cell culture, or some other repetitive and mundane lab task? Why not cheer things up with a podcast or two! Discover our top 10 favorite science podcasts for researchers, from Sawbones to The Life Scientific.
Read MoreA Beginner’s Guide to Biocuration—and How to Become a Biocurator
Discover more about biocuration, why it’s so important, and what it takes to become a biocurator. It turns out that biocuration as a career choice is easier than you might think!
Read MoreEthidium Bromide: Understanding the Dangers
This article reassesses the dangers of using ethidium bromide and compares some supposedly safer alternatives
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