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iPOND, Part 2: Why Should You Go Fishing with iPOND?

By Camilla S. Colding-Christensen | January 19, 2018

In part 1, ‘iPOND: Fishing for Proteins with DNA as Bait’ we went on a fishing expedition and learned how the iPOND technique can help us investigate the protein landscape of DNA synthesis. In this article, we will pit iPOND against a few other widely used techniques in order to answer the question: ‘Why should…

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Quantifying Individual Proteins Per Bacterial Cell

By Amanda Hurley | January 19, 2018

I’m a simple molecular biologist. It’s awesome how computational biologists use math to reduce and rebuild biological phenomenon. In my own way, I also like to reduce my observations to numbers. As a budding biochemist, I need to assemble and quantify the players in my pathway to truly understand it. In particular, I am interested…

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Using dbSNP and ClinVar to Classify Gene Variants

By Cindy Duarte Castelão | January 18, 2018

As we discussed previously, the gaps in our understanding of the human genome make variant classification an extremely difficult job. However, with each passing day our knowledge increases, and the tools to help us become increasingly more efficient. Let’s pick up where we left off in our first article about variants. After checking Ensemble to…

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