Techniques / Genomics & Epigenetics

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Article

Get Your Single Nucleotide Polymorphisms Straight From the Oven!

While it is true that there are some useful websites like SNPedia, or NCBI that can help you find rs codes for genetic variants, sometimes you need that info coming straight from the oven – particularly when...
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Article

Using a Genome Viewer to Scope your Sequencing Data

Now you've got great sequencing results, thanks to Nick's article on improving sequencing results. Now what? Well now you need some software (preferably free) to analyze your data. BioEdit is a good...
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Article

Get Started in Genome Editing with CRISPR

What was once a dream is now reality: You can now target and selectively edit the genome, thanks to the CRISPR/Cas9 technology. Changing forever how we approach biological questions. CRISPR/Cas9 is pretty...
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Article

Want NGS Success? Consider These Three Factors

NGS is still something a little scary for most operators. Mainly because of the price, which can make the pipette, in the hand of the best of us, shake a little with fear. And even though the protocols have...
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Omics Software Galore!

If you are looking for Omics software, then I suspect the G6G Directory of Omics and Intelligent Software need be your only stop. From the name it will come as no surprise that this website is a directory of...
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Article

Mysterious Plant miRNAs: What About Them?

Welcome to the last article in this series! Last, but by no means least, we will look at the importance of plant miRNAs and how they differ from their animal counterparts. When/How Were Plant miRNAs...
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Article

Nanopore Sequencing: An Update

People would have said that a USB sequencer not much bigger than a memory stick which could sequence genomes in 50kb+ read-lengths was impossible “’Star Trek’ technology!" Now, that futuristic technology is here.
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Article

Homology Terminology: Never Say the Wrong Word Again

I’ve noticed that there exists some ambiguity about the different terms relating to homology. I’ll try to break them down here, with significant help from Genome Biology.
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Article

Controlling Gene Expression with CRISPR Interference (CRISPRi)

The genome editing technology, CRISPR/Cas9, is well known for assisting researchers in manipulating the genome of target cells and has already been discussed in a few posts. This article is about repurposing...
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Article

How to Express Proteins Across Kingdoms: Prokaryotes vs Eukaryotes

In the sci-fi novel Terminal World by Alistair Reynolds, a planet consists of zones with defined characteristics of matter interactions on a subatomic level. These conditions permit different levels of...
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