Marketing
Join Us
Sign up for our feature-packed newsletter today to ensure you get the latest expert help and advice to level up your lab work.
Join Us
Sign up for our feature-packed newsletter today to ensure you get the latest expert help and advice to level up your lab work.
Andrew has been a freelance life science writer for more than 20 years. Worked for academic institutions, startup biotechs, major biopharmaceuticals. Agriculture editor, Genetic Literacy Project. He has an MS in Biotechnology from the University of Maryland, and a BA in Physical Anthropology from the University of Pennsylvania.
Share this article:
Bisulfite pyrosequencing is becoming a routine technique in molecular biology labs as a method to precisely measure DNA methylation levels right down to the single base. The technique allows for detailed and high resolution analysis of DNA methylation at specific genomic regions. How to detect the 5th base? Methylation of any of the four nucleotides…
For those of you who prepare your own DNA libraries, this article will cover the most critical aspects of library preparation to ensure a successful sequencing run. Previous Bite Size Bio articles have covered the basics of how 454 sequencing works, so give those a quick review if you are unfamiliar with the process. This video is also highly…
Find out how CRISPR-mediated gene activation (CRISPRa) and repression (CRISPRi) work and why you should consider using them in addition to your CRISPR knockouts.
Previously, I introduced the DNA microarray technology and described the principle behind it: hybridization between the nucleic acid sequence from the biological samples being examined and a synthetic probe immobilized and spatially arrayed on a solid surface, the microarray. In this article, I will explain how these probes are designed and positioned on the array. I…
Your DNA sequence can be put to good use fairly easily with Blast and Mega software. These programs can help in phylogenetic tree construction. You can ask questions like what is the evolutionary relationship between a set of sequences from different species? Or how have certain microbial strains arisen? Blast As any bioscientist probably knows,…
Discover how to check DNA quality for long-read sequencing using electrophoresis and why pipetting carefully is so important.
The eBook with top tips from our Researcher community.