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Search below to delve into the Bitesize Bio archive. Here, you’ll find over two decades of the best articles, live events, podcasts, and resources, created by real experts and passionate mentors, to help you improve as a bioscientist. Whether you’re looking to learn something new or dig deep into a topic, you’ll find trustworthy, human-crafted content that’s ready to inspire and guide you.
Choosing a PhD topic can be very hard. There are a lot of things to consider from the subject to the supervisor. Here are some tips to help you choose. Find out what you really like This is the first topic because it is the most important. My first advice would be to get some…
This article mentions of suicidal thoughts. If you are having thoughts of self-harm, I encourage finding someone to talk to. It can be a family member, friend, or professional counselor. Many countries also have suicide hotlines. Mental Health is often not a priority for institutions or individuals in academia. Making institutions friendlier will take time,…
The more experienced hands in your lab know that molecular biology is rarely just a journey from A to B. As a result, I’ve constructed this short workflow as an introduction to genomic molecular techniques.
BLAST is the most popular bioinformatics online tool. But in order to properly use it, you have to understand that is not just a search query against a database but something far more complicated, and the information you get back far more…precious!
Do you fear failure every time you do an experiment?Do you feel constantly stressed about obtaining poor results?Do you feel personally culpable when an experiment goes wrong?If you answered “yes” to any or all of these questions, you may be suffering from perfectionism. For a scientist, this is a particularly damaging trait that needs to…
One of the most exciting things about being a scientist is doing experiments that have never been done before. Unfortunately, this can also be one of the most daunting aspects of science. Read on to make taking on your next experiment less daunting.
Obtaining external funding for your project through an NIH grant is a coup at any career stage. However, obtaining one of these grants is much easier said than done. Here is some advice from someone who has been through it and lived to tell the tale.
Here are some ideas to make your liquid handling robot perform at its best.
Basic Local Alignment Search Tool (BLAST) remains the cornerstone of biological sequence analysis. When users have one or few queries, the data are easy to interpret based on the graphical output that the search provides. However, when you have to analyze hundreds or a few thousand queries, running graphical outputs can be computationally intensive, difficult…
I’ve recently been doing some lyophilization of biological extracts. While I was preparing for the experiment, I became interested in the number of different methods there are for drying, concentrating and storing samples: freezing, freeze-drying, rotary evaporation, centrifugal evaporation and blow down drying. Here is a brief description of each technique for biological sample storage…
Pat yourself on the back, you saw a post with the word “coding” in the title and you didn’t freak out or glaze over. That’s the first step. Coding seems to have such a stigma attached to it; people tend to think that it’s incomprehensible nonsense that they could never learn, and that it has…
In part one, I discussed the ‘how to’ of simply freezing samples and the basics of vacuum evaporation, often referred to as speed vacing. Now, we’ll have a look at two more complex sample storage techniques (at least in terms of equipment) for drying samples (lyophilizaton and rotary evaporation) and the simpler method of blow…
In Part 1 of this article, I introduced you to using code for basic image manipulation in ImageJ and working with the command recorder to expand your coding vocabulary. I covered how to make a simple macro, how to edit it and then save it to be run again another time. If you skipped the…
At a conference, a poster can be a great tool for drawing people into conversation. Not only do you have something to break the ice with, you can also get really useful feedback from a completely different perspective! To make sure you get the most out of your poster time it’s important to have a…
How do we decide whether our research is having an impact or not? Is there a way to quantify the effect or judge the quality of the articles? Read on to find out about the nuances behind “impact factor.”
Innovation is the essence of research and it is the fuel that keeps the research industry going. If it were not for inventions, the field of scientific research would have dropped dead long ago. However, simply innovating something is not sufficient. It is not the end of the road, but the beginning of it. Therefore,…
A number of studies have shown that work–life balance, as well as personal happiness, positively correlates with productivity, professional achievement and success. Looks like that happiness is not only a luxury but it might be a key ingredient for success.
In my first article on this topic we delved into what miRNAs are, how they are generated, and their function. Now, we are going to discuss how to identify miRNAs and their targets. Why Do You Want to Look at Something So Small Anyhow? miRNAs play a crucial role in most physiological processes. It’s not…
Stuck in a rut? Here are some useful nuggets you could implement in your day-to-day science life.
If I had a barrel of apples for each time I’ve heard one of my classmates or friends say, “Oh, I want to work in a lab, but I don’t know how to find one” I could build a moon base out of apples. Working as an undergraduate will help you land sweet internships, look…
Greetings, I’m a research student and I’m having a lot of trouble in finding the right antibodies for my study, because I need both monoclonal and polyclonal. And I need to start addressing some other international scientists. The problem is that I don’t know how to address the situation. If they indeed have antibodies that…
You can’t put it off any longer – you need to write your first manuscript. This task can seem daunting at first, but with a little organization and planning, you’ll soon be publishing.
Finishing my third year of grad school, I can’t help but notice what a balancing act it has been- research and relaxation, finances and fun, beer and…not beer? I wanted to write this article to advise incoming first years and veteran grad students – even those mysterious 7th year students- on graduate school and the…
To draw a convincing conclusion from your data, you cannot simply shoot for the standard significance cutoff. You also need to consider the statistical power, which is determined in part by the sample size in your experiment.
Read our top tips to help you get the most out of your scientific literature surveys.
Unless you are one of those rare breeds that do organization naturally, setting a system in place to archive your experiments takes practice and perseverance. It’s hard to imagine when you are doing an experiment for the 100th time that you will ever forget how to do it; but a year down the line, when…
Clinical Trial Coordinator, Clinical Study Coordinator, and Clinical Research Coordinator are all names for the same job and refer to the person responsible for the day-to-day running of human trials. Usually when I tell someone that I’m a Clinical Study Coordinator, they have no idea what that means. I guess it’s like when someone tells…
Need tips for surviving being the newbie of the lab, and what you can do to handle all the possible personality types you may encounter. Read on.
So it’s time to write up your thesis. By now, you probably consider yourself an expert on your topic or you hate the sight of it (or both!). Either way, hundreds of typewritten pages are all that stands between you and graduation/freedom. One of your first requirements will be to review the current knowledge on…
Given enough time, even the worst rookie research disasters seem amusing. It’s a comedy of errors that test our wit and our patience, but ultimately leave a lifelong impression on how to try experimentation a little bit differently the second time around. With that said, here are 5 brief stories of amusing things I’ve witnessed…
Whether as a summer intern, exchange student, MSc, PhD or post-doctoral student, working abroad can be one of the many perks of working within the sciences. Although these experiences will often require substantial planning in advance, there are funding opportunities and many receptive destinations around the globe. During my undergraduate degree, graduate studies hadn’t been…
Although bench work is an integral part of becoming a successful scientist, it is by no means the only part of it. It is often the uncredited skill set possessed by many seasoned scientists that make them so valuable to employers and to further research. In this article I will highlight the less obvious skills…
As a graduate student or PhD scientist you are likely to be surrounded by plenty of career advice and options – that is, if you’re interested in a career in academic research or the biotechnology and pharmaceutical industries. Those of us who aren’t sold on either of those fields are left wondering what other career…
The prospect of walking into the lab for the first time to do some ‘real’ research is hugely exciting. Ambitious thoughts fill your mind about what a brilliant research scientist you are about to become, making that all-important difference and saving the world. That is, until you step over the threshold and The Fear overcomes…
If you look closely, there’s a scenario that plays out frequently in labs across the world: A scientist sits hunched over dry ice searching exhaustedly through frozen boxes for one sample that has disappeared into the abyss. The tube or specimen in question was likely catalogued at some point in time. But, between then and…
I still remember the first time I stood in front of a crowd of about 35 people, including my brand new lab mates and professors, in my first ever lab meeting. My feet were as wobbly as ever, and all I wanted was a big boulder to hide behind, so my crazy, shaky legs would…
During my second year in graduate school, I (silently) started freaking about life post-PhD. I read voraciously about science writing, scientific editing and business consulting positions. I went to seminars offered by the career center at my school. But, I was still lost. Between all the pipetting and PCRs, I could not figure out what…
Last time we brushed up on cell referencing and constructing formulae to use Excel for some basic and some slightly more advanced calculations. This time we’re going to move on to using some built-in Excel functions and go through how to apply all that we’ve done so far to a worked example that is relevant…
Microsoft Excel can be a really powerful, useful tool for certain kinds of data processing and record keeping, and the chances are you probably don’t even know how to use half of the functions it comes with! That’s OK, personally, I find Excel a bit less user-friendly than Word, but also it’s a programme I…
You’re applying for your first tenure-track position, and you’ve heard that your dream department uses something called the h-index to decide who will get interviews. It’s an increasingly common scenario: institutions are now regularly using the h-index to help make hiring and promotion decisions, especially when they have to screen many applicants. For that reason,…
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