Techniques / Genomics & Epigenetics

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Article

RNA-seq: The Challenges to Diving Right In

It’s the hot new technique. With a single procedure, you can get information about all RNA transcripts at once! It sounds like a dream. While RNA sequencing (RNA-seq) has opened the door to exciting new...
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Sponsored Education

For Better NGS Assemblies, Use More Precise DNA Size Selection

It may not be intuitive that a sample preparation step like DNA size selection would have a significant impact on downstream data analysis, but NGS users have proven that it does. Indeed, the precision of your...
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Article

Genome Viewers/Editors – Three of the Best

Sometimes the wide view is the best so a good genome viewer is a must for every molecular biologist. We review three leading genome viewer packages to get you started..
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Webinar

All about miRNAs: Practical Tips, Advice, and Applications

In this webinar you will learn the tips and tricks necessary for you to successfully work with miRNAs, and how you can use them to further your research. The main points we will cover are: Tips and...
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Article

Where Did It All Go Wrong?! Quality Control For Your NGS Data

You’ve carefully collected your samples, extracted nucleic acids and made your first set of next-generation sequencing libraries. How are you going to know if the data you get back is any good and whether it...
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Article

Breaking Down the Assembly of Nucleic Acid Sequences

Microbiome—a term that has become a hot topic in recent years—has scientists of all disciplines wanting to know more. Microbes are everywhere. On any type of surface you can think of. Our physical make up,...
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Article

Anchored Multiplex PCR for Next Generation Sequencing

Anchored multiplex PCR (AMP) is a powerful method for amplifying minuscule amount of nucleic acids. Combined with Next Generation sequencing, AMP just might be what you need to identify genetic mutations.
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Article

Kiss your samples goodbye: Outsourcing your Next-Gen experiment

Genomic Science has come a long way since the early days of Sanger sequencing in the 1970’s. Today, there are jazzy new sequencing technologies that include fragment analysis, epigenetic sequencing,...
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Article

Sanger Sequencing: How the Genome Was Won

I’ve never run a sequencing gel in my life, but people around me did, and they spent a lot of time on getting it just right. Although the principle described by Sanger in 1975 sounds straightforward (1),...
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Article

Navigating the Sea of Human Genetics, Part I

Ahoy mateys! At my workplace we've recently become EXTREMELY excited about a resource called the HuGE Navigator. It's so great that it's going to take me a couple of articles to highlight its features. Hop on...
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