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histology

Vivid blue shapes on a dark background to show working positive controls for immunofluorescence
Microscopy and Imaging

5 Controls for Immunofluorescence: A Beginner’s Guide 

ByGauravi Deshpande

Achieving publication-quality immunofluorescence images is tricky. Learn what controls for immunofluorescence you can use to get them!

Read More 5 Controls for Immunofluorescence: A Beginner’s Guide Continue

Image of toilet tissue as a pun about tissue processing for histology
Microscopy and Imaging

Tissue Processing For Histology: What Exactly Happens?

ByMartin Wilson

Tissue processing for histology is a key step between fixation and embedding. We take you through the steps of tissue processing in this simple guide.

Read More Tissue Processing For Histology: What Exactly Happens?Continue

A polished cross-section of intricate rock as an abstract representation of the result of histology slide preparation
Microscopy and Imaging

How Histology Slides Are Prepared

ByNicola Parry

Ever wondered what magic happens to turn your samples into histology slides? Find out the 5 simple steps for histology slide preparation.

Read More How Histology Slides Are PreparedContinue

Abstract intricate represent hematoxylin and eosin staining.
Microscopy and Imaging

A Beginner’s Guide to Hematoxylin and Eosin Staining

ByNicola Parry

Discover what hematoxylin and eosin staining is used for and how it works, in this concise guide.

Read More A Beginner’s Guide to Hematoxylin and Eosin StainingContinue

Keys and a padlock to represent locking a sample in place after using fixatives for histology
Flow Cytometry

4 Fixatives for Histology and Cytometry. Perfect Your Preservation

ByDerek Davies

Learn about four fixatives for histology, which one you should pick, and how. Plus, get some top tips for perfect sample preservation.

Read More 4 Fixatives for Histology and Cytometry. Perfect Your PreservationContinue

An image of microscope that resembles a happy face to represent happy researchers following SEM sample preparation
Microscopy and Imaging

Scanning Electron Microscopy: 6 SEM Sample Preparation Pointers for Successful Imaging

BySaraswathi Sadasivan

Discover 6 critical scanning electron microscopy sample preparation points you need to know to get the best out of your SEM.

Read More Scanning Electron Microscopy: 6 SEM Sample Preparation Pointers for Successful ImagingContinue

Image of a mechanic thinking before fixing a car to represent thinking before performing histology fixation
Microscopy and Imaging

An Introduction To Fixation For Histology: Think Before You Fix!

ByMike Millar

How you fix your tissue or cells can affect your results, for better or for worse. Discover the key points to think about before undertaking your histology fixation.

Read More An Introduction To Fixation For Histology: Think Before You Fix!Continue

A bookshelf of old books to represent the history of histology
Microscopy and Imaging

A (very) Short History of Histology

ByMartin Wilson

Discover the history of histology, from the first mention of a cell in 1665 to the identification and development of various stains.

Read More A (very) Short History of HistologyContinue

Image of a girl surround by traps to represent avoiding histology mistakes
Microscopy and Imaging

Avoid These Pitfalls: Seven (Not So Deadly) Histology Sins

ByDr Jennifer Redig

Discover seven common histology mistakes and how you can avoid making them when performing your experiments.

Read More Avoid These Pitfalls: Seven (Not So Deadly) Histology SinsContinue

Kalidascopic image as a play on word for RNAscope
Microscopy and Imaging

New-ISH on the Block: Introduction to RNAscope®

ByChristina Lebonville

RNAscope is a new method of quantitative RNA in situ-hybridization that has taken laboratories by storm. Learn advantages over traditional techniques and how RNAscope works in this introduction article.

Read More New-ISH on the Block: Introduction to RNAscope®Continue

Artistic colorful stains to depict different stains used in histology
Microscopy and Imaging

The A to Z of Histological Stains

ByLakshini Mendis

From Alkaline phosphatase to Warthin-Starry, we take you through the various histology stains available.

Read More The A to Z of Histological StainsContinue

Image of colorful stains highlighting the various special stains for histology
Microscopy and Imaging

Special Stains for Histology: An Introduction and Basic Overview

ByNicola Parry

Get introduced to some of the special stains for histology and learn some top tips for getting great results.

Read More Special Stains for Histology: An Introduction and Basic OverviewContinue

image of paraffin wax beauty treatment to highlight alternatives to tissue embedding including cryo and resin embedding
Microscopy and Imaging

Alternatives to Paraffin: Cryo and Resin Embedding for Histology

ByCatriona Paul

Looking for paraffin alternatives for tissue embedding? Find out the benefits of cryo and resin tissue embedding and how they work.

Read More Alternatives to Paraffin: Cryo and Resin Embedding for HistologyContinue

Imgae of hand choosing between different colors, representing the differnet choices of counterstains for immunohistochemistry
Microscopy and Imaging

Counterstaining for Immunohistochemistry: Choices, Choices…

ByCatriona Paul

Counterstaining can have a big impact on your histology result. This short guide will introduce you to some available counterstains providing you with a few more choices.

Read More Counterstaining for Immunohistochemistry: Choices, Choices…Continue

Image of pouring milk as it can be used for blocking non-specific staining
Microscopy and Imaging

Immunohistochemistry Basics: Blocking Non-Specific Staining

ByDr Jennifer Redig

Achieving a good immunohistochemistry signal-to-noise ratio involves many factors, including a good blocking protocol. Read on to learn about blocking non-specific staining in IHC.

Read More Immunohistochemistry Basics: Blocking Non-Specific StainingContinue

image of masks to represent unmasking antigens
Microscopy and Imaging

Antigen Retrieval Techniques For Immunohistochemistry: Unmask That Antigen!

ByCatriona Paul

Did you know fixation can mask antigen sites in your sample? Discover how you can unmask them and get your signal back on track!

Read More Antigen Retrieval Techniques For Immunohistochemistry: Unmask That Antigen!Continue

Image of an iron as a pun of how prussian blue detects iron in samples
Microscopy and Imaging

Prussian Blue- A Histology Stain For Iron

ByNicola Parry

Want to detect iron in your samples? You need Prussian blue! Discover the incredible sensitivity of this stain and how to use it.

Read More Prussian Blue- A Histology Stain For IronContinue

Image of a red powder to represent the color of congo red stain
Microscopy and Imaging

Congo Red – A Special Stain For Alzheimer’s Disease

ByNicola Parry

Discover interesting facts about Congo red and it can help us understand Alzheimer’s disease.

Read More Congo Red – A Special Stain For Alzheimer’s DiseaseContinue

Image of bacteria to represent how to detect bacteria with acid-fast stain
Microscopy and Imaging

Acid Fast: A Histology Tool To Detect Bacteria and TB

ByNicola Parry

Acid-fast stain (AF) is a special staining technique used in the histology lab. Discover which bacteria this stain detects, the history behind it, and how it works.

Read More Acid Fast: A Histology Tool To Detect Bacteria and TBContinue

Image of a young man showing his back to highlight how periodic acid Schiff stains polysaccharides such as glycogen
Microscopy and Imaging

Why Pick PAS for Histology?

ByNicola Parry

Periodic acid-Schiff (PAS) is a commonly used special stain in the histology lab. Find out more about what this stain detects and how to use it.

Read More Why Pick PAS for Histology?Continue

Man holsing a paintbrush with paint all up the wall to represent troubleshooting histochemistry when things go wrong
Microscopy and Imaging

Troubleshooting Immunohistochemistry

BySteffi Magub

If your immunohistochemistry is not working quite as expected, don’t fret. Check out this comprehensive guide to troubleshooting immunohistochemistry.

Read More Troubleshooting ImmunohistochemistryContinue

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