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We show you how to read a scientific paper efficiently to make the most of your reading time.
P-value abuse directly contributes to one of the biggest problems facing the scientific community: the prominence of false-positive results in the published literature. Contrary to popular interpretation, the p-value doesn’t indicate the likelihood that the observed result was due to chance. There are important qualifications to p-value interpretation. Moreover, the p-value cannot directly speak to…
To draw a convincing conclusion from your data, you cannot simply shoot for the standard significance cutoff. You also need to consider the statistical power, which is determined in part by the sample size in your experiment.
In the last years, the need for using statistical testing in bioscience has grown exponentially and so has the development of statistical software. It is now common that everyone is using some sort of stats in their basic research. Among the skillful biostatisticians, R is the most popular software for data analysis, but not all…
When it comes to data analysis and interpretation, you need to be very clear about the meaning of a given p value and be aware of all its intrinsic limitations.
Part of my job in running a core flow cytometry facility is to make sure that the experiments that my users run have been optimised. But that optimisation can be split up into several areas. The first area is experimental planning: What do you want to know? Can you do this by flow cytometry? And…
No matter how we make measurements, there will be variation (a spread of data). Take 100 people and ask them to guess your age and you will get a range of results: some will be too low (excellent!), some too high (not so good!). It is the same with any of our laboratory experiments –…
One of the best parts of R is how extensible it is. Over the years, the community has put together hundreds (thousands?) of amazing packages to make your workflow easier. The downside of this wealth is that it can be hard to find packages that do exactly what you want! Therefore, I’ve put together a…
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