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DIY

A box of tools to represent getting the latest microscope technology by building your own.
Equipment Mastery and Hacks

Getting the Latest Microscope Technology into Your Lab: To Build or To Buy?

ByVaidyanathan Subramaniam

Discover whether it’s better to build or buy the latest microscope technology for your lab. This article weighs the advantages of custom builds against the ease and reliability of purchasing from vendors, helping you make the best choice for your research needs.

Read More Getting the Latest Microscope Technology into Your Lab: To Build or To Buy?Continue

Wooden blocks spelling DIY DNA for Build your own PCR machine.
PCR, qPCR and qRT-PCR

How to Build Your Own PCR Machine

ByOlwen Reina

You can build your own PCR machine using tools and equipment you can get easily and without breaking the bank. Well, what are you waiting for?

Read More How to Build Your Own PCR MachineContinue

Neon coloured hexagon to represent chemiluminescence in how to make ECL reagent
Protein Expression and Analysis

How To Make ECL Reagent: 4 Ingredients, Better Blots

BySteffi Magub

ECL is an expensive reagent. Why not learn how to make ECL yourself? This cheap and simple option will give you better blots more often!

Read More How To Make ECL Reagent: 4 Ingredients, Better BlotsContinue

A hand in rubber gloves holding a selection of scalpels for performing various DNA gel extraction methods.
Basic Lab Skills and Know-how

Kit-Free DNA Gel Extraction Methods: 3 Old School Protocols to Save Money

ByVicki Doronina

Kits for DNA gel extraction are a great way to save time in the lab, but they are costly and produce much plastic waste. Discover three easy kit-free DNA gel extraction methods that can save you money and reduce waste in the lab.

Read More Kit-Free DNA Gel Extraction Methods: 3 Old School Protocols to Save MoneyContinue

A person holding power tools doing DIY to depict making DIY chemically competent cells
DNA / RNA Manipulation and Analysis

How to Make Your Own Chemically Competent Cells

ByAlex Chen

We’ll show you how to make a DIY stock of chemically competent E. coli, the workhorse in the molecular biology laboratory.

Read More How to Make Your Own Chemically Competent CellsContinue

An image of ingredients to depict a method to make your own ECL
Protein Expression and Analysis

How To Make Your Own ECL

BySteffi Magub

ECL can be an expensive reagent in a lab. Why not make your own? Hopefully, this quick, simple and cheap solution will be of help to you!

Read More How To Make Your Own ECLContinue

A cartoon of a man sitting at a computer to depict searching for the Top 10 PCR websites.
PCR, qPCR and qRT-PCR

Top 10 websites to help you with your PCR experiments

ByDr. Karen O'Hanlon Cohrt

When you’re trying to solve a PCR problem, you’ll probably resort to a Google search at some point or another. Here’s a list of the Top 10 go-to websites to help solve your PCR problem.

Read More Top 10 websites to help you with your PCR experimentsContinue

An image of a fun ride to depict easy ways to wreck a centrifuge.
Equipment Mastery and Hacks

5 Ways to Wreck Your Centrifuge

ByJason Erk

Here are five unfortunately easy ways to wreck a centrifuge, and how to make sure it never happens in the first place!

Read More 5 Ways to Wreck Your CentrifugeContinue

An image of petri dishes to depicts cell culture on a budget
Cell Culture

Cell Culture on a Budget: Simple Homemade Fixes

ByDr Rebecca Tirabassi

Mammalian cell culture can easily deplete grant funds. Sometimes you can alter protocols to use expensive reagents sparingly. Here are a few tips!

Read More Cell Culture on a Budget: Simple Homemade FixesContinue

An image of monster eyes to depicts how to clean a water bath.
Equipment Mastery and Hacks

How to Clean a Water Bath (When You Can’t Avoid it Any Longer)

ByCristy Gelling

Here’s a quick guide to cleaning and maintenance, to help you overcome your fears of the monsters lurking in your water bath.

Read More How to Clean a Water Bath (When You Can’t Avoid it Any Longer)Continue

An image of neon signs to depict a menagerie of miniprep methods.
DNA / RNA Manipulation and Analysis

A Menagerie of Miniprep Methods

ByLiam Thompson

There’s more than one way to do a plasmid miniprep. Here are 5 to add to your molecular biology arsenal.

Read More A Menagerie of Miniprep MethodsContinue

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