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Lynnea Waters

Lynnea has a PhD in Molecular Biology from University of California, Los Angeles, and is currently working as Medical Communications Senior Manager – Oncology at Amgen.

Institution : Amgen
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Articles by Lynnea Waters

An Introduction to Chimeric Antigen Receptors (CARs)

An Introduction to Chimeric Antigen Receptors (CARs)

By Lynnea Waters | June 19, 2018

You may have heard about a breakthrough cancer therapy that engineers patient’s immune cells to fight their cancer using  chimeric antigen receptor (CAR)-T cells. If you don’t live in the world of immunology, you may not know what a CAR is, or what it is used for. Here you’ll find a brief guide to CARs,…

What's in Your Cell Culture Medium?

What’s in Your Cell Culture Medium?

By Lynnea Waters | October 25, 2017

Anyone who has performed mammalian cell culture will recognize the typical media recipe: 1 bottle of DMEM, 10% serum, a few other magical ingredients, throw it together and put it on your cells to keep them alive and happy. However, do you know what each ingredient does? Let’s look at the common ingredients in cell…

How UV Radiation Causes DNA Mutations

How UV Radiation Causes DNA Mutations

By Lynnea Waters | September 19, 2017

We all know that we are supposed to put on sunscreen in the summer months to protect ourselves from skin cancer, and the connection between sun exposure and cancer is well documented (Koh et al., 1996; Armstrong and Cust, 2017). UV-A and UV-B rays from the sun interact with the DNA in our skin and…

How to Properly Streak a Single Bacterial Colony

By Lynnea Waters | September 1, 2017

Bacteria are the workhorses of many molecular biology laboratories, and mastering the basic techniques to manipulate bacteria is an important stepping-stone towards achieving great results. When isolating DNA from bacteria, it is important to start with a single colony to ensure a homogenous population of bacteria in your culture. Isolating a single bacterial colony from…

Demystifying the Flow Cytometry Optics System: A Peek Under the Hood

Demystifying the Flow Cytometry Optics System: A Peek Under the Hood

By Lynnea Waters | November 24, 2016

To many users, the flow cytometer is a magic box: put in cells, get out data. You click the button to tell it which colors to look at without much thought about how the machine does this. However, not all fluorophores are created equal—some configurations might exclude the spectrum you’re really looking for. Here’s a…

great talk

How to Give a Great Scientific Talk and Engage Your Audience

By Lynnea Waters | September 14, 2016

We have all been to awful talks—hours of slides crammed with data, given by presenters who assume you know as much as they do. But hopefully you’ve also seen a great scientific talk. A talk in which you’re walked through a story, eagerly anticipating each question and data point, until you finally reach a conclusion…

cell cycle analysis

Cell Cycle Analysis by Flow: DNA Stains and Beyond

By Lynnea Waters | September 8, 2016

While you can observe mitotic cell cycle progression using immunofluorescence, flow cytometry is a great tool to delineate details that aren’t apparent by chromosomal morphology alone. DNA stains are a great way to get a general idea of what your cells are up to. There are also a number of other stains you can use…

mass spectrometry contaminants

Common Mass Spectrometry Contaminants: I Messed It Up So You Don’t Have To!

By Lynnea Waters | September 1, 2016

Through many trials, and lots of error, I learned that there are many considerations for mass spectrometry that might not be obvious to you as a molecular biologist. Common contaminants, even in small quantities, can mask important peaks in your mass spec data and have a huge impact on the final results.

primary murine B cells

The Care and Keeping of Primary Murine B Cells

By Lynnea Waters | August 11, 2016

So you want to work with mouse B cells? Primary murine B cells are a difficult, yet fascinating system to work with and can help deepen your understanding of an immunological system. You can study many things with primary B cells, including: immune activation antibody production cell-cell interactions between immune cells and immune phenotype These…

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