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CRISPR inhibition.

Image of DNA transcriptio to show how CRISPR can modify gene expression using CRISPRa and CRISPRi
Genomics and Epigenetics | Sigma-Aldrich® Advanced Genomics

Why You Should Consider Adding CRISPRa and CRISPRi to Your Toolbox

BySigma-Aldrich® Advanced Genomics

Find out how CRISPR-mediated gene activation (CRISPRa) and repression (CRISPRi) work and why you should consider using them in addition to your CRISPR knockouts.

Read More Why You Should Consider Adding CRISPRa and CRISPRi to Your ToolboxContinue

DNA being modified using a tool to represent modified CRISPR nuclease formats
Genomics and Epigenetics | Sigma-Aldrich® Advanced Genomics

How to Understand CRISPR Formats and Their Applications

BySigma-Aldrich® Advanced Genomics

Find out how modified variants of CRISPR nucleases provide gene editing with reduced off-target effects and can even control gene expression without altering the DNA sequence.

Read More How to Understand CRISPR Formats and Their ApplicationsContinue

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