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Justin Demmerle

I’ve come from the University of Chicago to Oxford to work with structured illumination microscopy in the Schermelleh lab. I’m particularly interested in the three-dimensional organization of the nucleus and spatial regulation of chromatin architecture.

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Articles by Demmerle

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A Semi-intelligible Explanation Of Structured Illumination Microscopy (SIM)

By Justin Demmerle | June 18, 2013

If you found our previous section on super resolution interesting, you may be curious for a more detailed explanation behind some of the techniques. Introduction to this counterintuitive method Of the super-resolution microscopy techniques, structured illumination microscopy (SIM) is arguably the most counterintuitive to grasp. Of course, that’s what makes it so much fun! To understand how…

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Overcoming The Limits Of Light: A Guide To Super Resolution Microscopy Part 2

By Justin Demmerle | April 16, 2013

In Part 1, we looked at diffraction limits and how these can be overcome using Super-Resolution Microscopy techniques. We covered Single Molecule Localization Techniques, Structured Illumination Microscopy and Stimulated Emission Depletion. In this second part, we’ll take a look at Near-Field and Dual Objective Methods as well things to consider before buying a system. Near-field…

Overcoming The Limits Of Light: A Guide To Super Resolution Microscopy Part 1

Overcoming The Limits Of Light: A Guide To Super Resolution Microscopy Part 1

By Justin Demmerle | April 2, 2013

If you’re reading our Microscopy and Imaging Channel here on BitesizeBio, you might have heard about the new techniques which fall under the umbrella of ‘Super-Resolution Microscopy’. In her recent article, Cynthia introduced us to the limits of resolution and how this can be overcome. Question time You may have more questions; What are the…

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