Genomic Analysis of Single Cells: The Benefits of Being Single

Genomic Analysis of Single Cells: The Benefits of Being Single

You don’t need to be told about how next generation sequencing technologies have revolutionized the way we study the genome and the epigenome. Whether you want to look at transcription (RNA-seq), translation (Ribo-seq) genomes (DNA-seq), interactions of proteins and DNA (ChIP-Seq) or to study epigenetic features such as methylation (whole genome bilsulfite sequencing) there are…

A Quick-Fire Guide to Shotgun Sequencing (and Assembly)

A Quick-Fire Guide to Shotgun Sequencing (and Assembly)

“Making the simple complicated is commonplace; making the complicated simple, awesomely simple, that’s creativity.” –  Charles Mingus   Next Generation Sequencing (NGS) technology has boomed in recent years, allowing researchers to probe further into the workings of the genome. According to the theory of simplicity, it is the simple principles on its basis that make…