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You might have heard of the Cre-loxP system even if you are not directly working with genetic manipulation. The Cre-loxP system is a ubiquitous technology for genetic manipulation and a mainstay in mouse research labs. For a recombination-based approach to markerless gene deletion in bacteria, see old reliable: two-step allelic exchange. The Two Main Components of the Cre-LoxP…
The mouse is the favored model organism for life science researchers so much so that mice account for about 95% of all lab animals used in research. The striking similarities between the human and mouse genomes, ease of genetic manipulation and the uniformity achieved through inbred mating makes them ideal crusaders in the quest for…
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