Jennifer Cable
Jennifer received a PhD in Biochemistry from the University of North Carolina.
Articles by Jennifer Cable
Welcome to part two of “What Can NMR Do For You?”, a three-part series in which we see how you can use simple NMR experiments in your research. In part one, we went over some key points to keep in mind when doing NMR on proteins and DNA, such as sample preparation, and saw how…
There are six little words that can instill both excitement and trepidation in the heart of a graduate student: “No one’s ever done this before.” What those words really mean, of course, is “No one’s ever published this before,” and you are either standing at the edge of a great discovery or a chasm of…
Having done my PhD work in an NMR lab, I sometimes feel like NMR doesn’t get the credit it deserves. As a structural tool, it always seems to play second fiddle to crystallography, and not many people seem to know about all of the different types of information that NMR can give you.> So why…
When working with proteins, one key part of any good assay is accurately determining how much protein you have. Accurate quantification is obvious important if, for example, you’re trying to determine a binding constant or measure enzyme kinetics; but even if you’re doing something more qualitative, having a good idea of how much protein you…
When purifying a protein, it’s important to keep your protein happy. If you are going to use the protein in binding and activity assays, such as the surface plasmon resonance (SPR) technique, then your protein needs to be soluble and active. For success in these experiments, it is crucial that you create a buffer that…