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Jennifer Cable

Jenn received a PhD in Biochemistry in June 2011 from the University of North Carolina. Her research interests include examining the relationship between protein structure and dynamics and function. Since getting her PhD, Jenn has moved to New York City to embark on an exciting science writing career and is currently sharing her interests in protein structure with middle school students to teach them about structure-based drug design.

Articles by Jennifer Cable:

What Can NMR Do For You? — Part Two

Welcome to part two of “What Can NMR Do For You?”, a three-part series in which we see how you can use simple NMR experiments in your research. In part one, we went over some key points to keep in mind when doing NMR on proteins and DNA, such as sample preparation, and saw how…

29 Oct 2012 Analytical Chemistry and Chromatography Techniques

Turn That Frown Upside Down! or, How to Publish Your Negative Results

There are six little words that can instill both excitement and trepidation in the heart of a graduate student: “No one’s ever done this before.” What those words really mean, of course, is “No one’s ever published this before,” and you are either standing at the edge of a great discovery or a chasm of…

11 Apr 2012 Writing, Publishing and Presenting

What Can NMR Do For You? – Part One

Having done my PhD work in an NMR lab, I sometimes feel like NMR doesn’t get the credit it deserves. As a structural tool, it always seems to play second fiddle to crystallography, and not many people seem to know about all of the different types of information that NMR can give you.> So why…

02 Mar 2012 Analytical Chemistry and Chromatography Techniques

How to Measure Protein Concentration More Accurately

When working with proteins, one key part of any good assay is accurately determining how much protein you have.  Accurate quantification is obvious important if, for example, you’re trying to determine a binding constant or measure enzyme kinetics; but even if you’re doing something more qualitative, having a good idea of how much protein you…

30 Nov 2011 Basic Lab Skills and Know-how

How to Design the Perfect Protein Purification Buffer

When purifying a protein, it’s important to keep your protein happy. If you are going to use the protein in binding and activity assays, such as the surface plasmon resonance (SPR) technique, then your protein needs to be soluble and active. For success in these experiments, it is crucial that you create a buffer that…

03 Nov 2011 Protein Expression and Analysis