Reliable concentration and purity measurements of DNA, RNA, and protein samples form the foundation of successful cloning, qPCR, NGS library prep, western blots, and countless other molecular biology workflows.
However, not every lab has access to premium, high-cost instrumentation. Research and teaching labs operating under tight budgets still need reliable quality control (QC) data, but may lack the resources.
The Helium 1 µL UV spectrophotometer is designed to make reliable microvolume UV spectrophotometry more accessible, so that you don’t have to risk a large initial investment to get trustworthy performance.
In practice, QC measurements get repeated throughout an experiment at key decision points (and where accuracy matters but time is limited).
In busy labs, QC instruments are often shared between multiple users, creating queues and interruptions at critical moments. Teaching labs add further pressure, with many users of varying experience levels and limited time for training.
QC shouldn’t become a bottleneck that slows experiments or introduces uncertainty. Researchers and students need reliable results free of unnecessary complexity or delays.
What you really need is an affordable, reliable checkpoint: a robust and easy-to-use instrument that skips the setup and calibration, giving you clear insight to support your decision on whether to proceed to the next stage of your experiment.
Built for Daily Use in Demanding Environments
Busy labs need instruments that can withstand daily use by multiple researchers or students without breaking down or requiring constant recalibration.
The Helium 1 µL UV spectrophotometer is engineered for reliability and backed by DeNovix’s renowned support, granting exceptional value for both research and teaching environments. Its maintenance-free design ensures lifetime consistency with no recalibration required.
For labs on strict budgets, this predictable operation makes the Helium accessible to teams that previously relied on shared equipment or less precise alternatives.
Affordable Access to Premium DeNovix Technology
The Helium is built on the same core DeNovix technology platform that powers the premium DS-11 Series: an established system trusted by thousands of researchers worldwide.
This shared technological foundation means that, while the Helium is a more budget-friendly option, it is still able to provide the accuracy and reliability associated with the wider DeNovix portfolio.
Easy Biomolecule Quantification in Under Five Seconds
The Helium delivers results in under five seconds. Simply pipette a microvolume of your sample directly onto the measurement surface (no cuvettes needed). This speed means you can incorporate QC steps readily into your workflow without causing delays.
DeNovix EasyApps™ software combines an intuitive interface with powerful functionality, making the Helium easy to use from day one.
SmartPath™ technology integrates hardware and software to provide real-time optimization of every sample, ensuring accurate daily measurements you can trust.
The microvolume, consumable-free design reduces waste and minimizes training requirements—perfect for high-throughput research and teaching labs.
For multi-user environments, simplicity is essential. The Helium’s clear workflow and intuitive interface help reduce training time and user error, meaning students and new lab members can generate reliable results quickly and confidently.
Key features
- SmartPath™ technology – Real-time sample optimization for accurate, reliable measurements
- Biomolecule Range – Quantify nucleic acids (dsDNA, ssDNA, RNA) and protein (BSA, IgG, custom) with as little as 1 μL of sample
- Broad Quantification Range – Measure concentrations of 2 – 1,600 ng/µL (dsDNA); 0.1 – 48 mg/mL (BSA)
- Quality Control Built-In – 260/230 and 260/280 purity ratios for sample assessment
- Data Management Options – Store up to 2,000 samples; easily review and export to USB or label printer
- Simple to use Interface – Ideal for research and teaching labs
Together, these features make the Helium a practical, everyday QC solution for modern molecular biology laboratories.
Find out more about the Helium 1 µL UV Spectrophotometer by clicking here.
DeNovix products are for research use only.

