by Shoba on May 28, 2009

I had previously talked about the basics of cell-free protein synthesis and ways to improve yields from the technique. But recently I came across an article describing a technology that promises to dramatically improve the (read on...)

by Dan on September 15, 2008

For something a bit more on the fun side, at least if you enjoy a pint of beer now and then - a genomic-based study has reconstructed the origins by hybridization of the lager yeast Saccharomyces pastorianus, published in the (read on...)

by Dan on August 18, 2008

Two recent articles that I came across clearly illustrate ways in which cellular asymmetry is both easily established by basic factors, and provide the basis for processes like cellular polarity and aging. One cannot claim with (read on...)

by Nick on April 24, 2008

FEBS Letters is this month carrying out an interesting experiment that could make literature searching easier for both humans and computers. The experiment centres on Structured Digital Abstracts (SDA). SDA are extensions of the (read on...)

by Dan on March 20, 2008

A minireview recently in Genomics caught my eye with the title Coexpression, coregulation, and cofunctionality of neighboring genes in eukaryotic genomes that sounded just like a passage that I recalled from Richard Dawkins' The (read on...)

by Dan on February 8, 2008

Just Science week has been fun, reading four recent journal articles on focal adhesion kinase (FAK). It has helped me refresh myself on FAK as I got back to writing fellowship applications - although it had the added effect of (read on...)

by Dan on February 7, 2008

After the past three days of blogging focal adhesion kinase (FAK), each focusing on an important regulator of cell adhesion dynamics and cell motility, I'm going to turn my attention to phosphatidyl inositol-3 kinase (PI3K). (read on...)

by Dan on February 6, 2008

In keeping with this week's trend of just science blogging on FAK, let's take a look at another critical protein-protein interaction - this time with the scaffolding protein Paxillin. Specifically, how do FAK and Paxillin (read on...)

by Dan on February 5, 2008

Yesterday, I ended a post about FAK, Pyk2 and regulation of RhoA activity by asking "So, what about Rac regulation by [FAK] and Pyk2?" Today, let's discuss a paper relating FAK/Pyk2 function studies on Rac1: Regulation of (read on...)

by Dan on February 4, 2008

Focal adhesion kinase is an important signaling molecule in integrin-mediated cell signaling and cell adhesion. In FAK genetic knockout (FAK-null) cells, its closely homologous relative proline-rich kinase (Pyk2) is upregulated (read on...)