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Live Webinar Date: 13 June, 2019

How to Weigh Molecules with Light Using Mass Photometry

Start Time:

Berlin Time: 4:00 pm
Boston Time: 11:00 am
San Diego Time: 8:00 am

Webinar Summary

In this webinar, you will learn:

  •    How mass photometry offers a universal way to study biomolecules
  •    The strengths and limitations of mass photometry
  •    How to use mass photometry to:

1)    accurately determine the degree of heterogeneity of a sample

2)    quantify the strength and kinetics of molecular interactions

3)    optimize conditions for sample stability and molecular interactions

4)    quantifying self-assembly

5)    precise characterization of molecular concentration

Mass photometry is a natural evolution of interferometric scattering microscopy that offers a universal way to study biomolecules that will change how research is performed across many fields of biomedical science.

 

Abstract

Physiological and pathological processes are mediated by the interactions between different biomolecules. Studying these functional and malfunctional associations is key to elucidating the molecular mechanisms of life, and to develop new means to combating disease.

Successful in vitro studies of protein and macromolecular function rely heavily on well-defined samples. The purity, homogeneity, structural integrity, and activity of all components of these samples must be quantified.

While there are numerous established methods for sample quality assessment, mass photometry can accurately measure the mass of individual molecules in solution without the need for any labels. Mass photometry is a completely new technology that enables researchers to characterize biomolecular composition, structure, and dynamics.

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Sponsored By

Presented By

Prof Philipp Kukura

University of Oxford
Speaker Profile

Philipp Kukura is Founder and Director of Refeyn Ltd and Full Professor of Chemistry at the University of Oxford. His research focuses on the development and application of novel optical methodologies aimed at revealing structure, energetics and dynamics and nanoscopic and molecular length scales. He has received support from the ERC in the form of Starting and Consolidator grants and has received awards from the Royal Society of Chemistry (Harrison-Meldola and Marlow), the European Biophysical Society and the Royal Society, as well as being awarded the Klung-Wilhelmy Science Award and the UK Blavatnik Award.

Live Webinar Date: 13 June, 2019

How to Weigh Molecules with Light Using Mass Photometry

Start Time:

Berlin Time: 4:00 pm
Boston Time: 11:00 am
San Diego Time: 8:00 am