Skip to content

Comprehensive flow cytometry profiling of the immune system in COVID-19 convalescent individuals

Available On Demand


Marjorie Pion

Marjorie Pion

Principal Investigator
Instituto de Investigación Sanitaria Gregorio Marañón

In this webinar, you will discover:

  • what is currently known about the potential long-term dysregulation of the immune system that may be induced by SARS-CoV-2 infection, and its implications;
  • how flow cytometry immune profiling can be used to track alterations in the immune system over time;
  • the results of deep analysis of the immune system of COVID-19 recovered individuals, including new data on several immune system alterations;
  • how these findings may lead to the identification of important prognosis markers for SARS-CoV-2 re-infection or the presence of long-term symptoms in some individuals.

SARS-CoV-2 has infected more than 200 million people worldwide, with more than 4 million associated deaths. Although more than 80% of infected people develop asymptomatic or mild COVID-19, SARS-CoV-2 can induce a profound dysregulation of the immune system. It is therefore important to investigate if clinically recovered individuals exhibit long-term dysregulation of the immune system which could constitute a risk factor for re-infection and the development of other pathologies.

Join this webinar to see the results of a deep analysis of the immune system in 35 COVID-19 recovered individuals previously infected with SARS-CoV-2 compared to 16 healthy donors, by flow cytometry immune profiling. Samples from COVID-19 individuals were analyzed from 12 days to 305 days post-infection. Alterations in the values of some T-cell, B-cell, and innate cell subsets were observed 10 months post-infection in recovered COVID-19 patients compared to healthy controls. Moreover, increased levels of circulating follicular helper type 1 (cTfh1), plasmablast/plasma cells, and follicular dendritic cells (foDC) was found in recovered COVID-19 individuals, indicating that the Tfh-B-foDC axis might be functional to produce specific immunoglobulins 10 months post-infection.

These data indicate that the presence of this axis and the accompanying immune system alterations could constitute prognosis markers and could play an important role in potential re-infection or the presence of long-term symptoms in some individuals.

Webinar brought to you by

Beckman Coulter Life Sciences

Enter your details to view this webinar on-demand

[Beckman] Webinar 28-feb-22 Comprehensive flow cytometry

  • Please keep me informed about Beckman Coluter webinars, products, goods and services including products, goods, or services from Beckman Coulter's related companies.

  • By submitting this form I confirm that I have reviewed and agreed with the Beckman Coulter privacy policy and terms of use. I also understand my privacy choices as they pertain to my personal data as provided in the privacy policy under "Your Privacy Choices".

All Bitesize Bio emails contain an unsubscribe link. You can review our privacy policy, cookie policy and terms and conditions online.

Share this to your network:
Scroll To Top