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Chiu-An-Lo

Articles by Chiu-An-Lo:

A Crash Course in CRISPR-Cas9 Editing in Drosophila

CRISPR-Cas9 has become a magic tool for molecular biologists, transforming genetic engineering from a once unbelievable dream into tangible reality. Today, you can easily edit primary cells or cell lines within a few weeks with well-established protocols or others’ hands-on advice. However, no matter how many success stories you find online or hear at seminars…

20 Jun 2017 Genomics & Epigenetics

Fluorescent Western Blotting: Lowdown and Advantages

In this article, you will be introduced to the world of fluorescent western blotting. Firstly, we will compare fluorescent and chemiluminescent western blotting. Then, we will learn how infrared fluorescent western blotting can give you truly quantitative and reproducible results. Lastly, we’ll look at the many advantages of fluorescent western blotting, including the possibility to multiplex. Importantly,…

11 Apr 2017 Protein Expression & Analysis

How Many Data Points Do I Need For My Experiment?

To draw a convincing conclusion from your data, you cannot simply shoot for the standard significance cutoff. You also need to consider the statistical power, which is determined in part by the sample size in your experiment.

09 Jul 2016 Lab Statistics & Math

3 Common Myths About p Value: Alternatively Never, Ever Rely on it for Data Interpretation

When it comes to data analysis and interpretation, you need to be very clear about the meaning of a given p value and be aware of all its intrinsic limitations.

09 Jul 2016 Lab Statistics & Math

GeneDig: An Easy-to-use Genome Browser for Bioscientists

The recent advancement of next generation sequencing technology and the development of novel gene editing tools, such as CRISPR-Cas9, have revolutionized research in genetics. In this golden era of molecular biology, knowing how to dig and navigate through all the enormous sequence information is an essential skill for most molecular biologists. However, to obtain facile…

04 May 2015 Genomics & Epigenetics