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Derek Bickhart

I am a US postdoctoral fellow working with next-generation sequencing data derived from many livestock and domestic animal species. While my formal training has been in Molecular Biology, a shortage of dedicated Computational Biologists in my graduate school lab forced me to pick up programming and data analysis skills. I haven’t looked back since. When I am not working with large sequence-derived datasets, I also build computers and read history books.

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Articles by Bickhart

Bioinformatics for NGS: Open Source or Proprietary?

By Derek Bickhart | December 6, 2012

As many who have worked with sequence data can tell you, the biggest bottleneck in publishing papers based on sequence data is the analysis step. Most researchers are faced with a dilemma when they receive sequence data for the first time: “do I try to use these free open source programs or do I shell…

DNA isolation

Garbage in, Garbage out? Quality Control of Your NGS Data

By Derek Bickhart | October 25, 2012

So, you’ve just received a call from the core facility that you hired to prepare and sequence your libraries. The facility director tells you that the sequence data from your next generation sequencing (NGS) experiment does not look good. You panic and, perhaps, let loose a scream of frustration—aaarrrrggghhhh! This project was going to be…

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