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Aparna Natarajan

Aparna holds an MS in Molecular Biology, Biochemistry and Microbiology from the Southern Illinois University School of Medicine.

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Articles by Aparna Natarajan

Look To The Stars: What Astronomy Can Teach Us About Handling NGS Data

By Aparna Natarajan | September 12, 2013

It is no news to anyone in the genomics field that as we are constantly accumulating and producing big data, we are in big need to manage the data better. As we move towards personalized medicine, there is the need to integrate epigenetic, genomic and transcriptome data together. It is important more than ever to…

The HeLa Cell Line Genome: A Spark To Light The Debate On The Ethics Of Personal Genomics

By Aparna Natarajan | May 9, 2013

For the past six decades, HeLa cells have been vital to making groundbreaking research in science. Scientists have made countless passages from them and shipped them worldwide, but did not put much thought into how they originally established. Scientific discovery and faith healing Rebecca Skloot gave the cells a life and a history in her…

Another Revolution In NGS? Exciting Times Ahead With Nanopore Sequencing Technology

By Aparna Natarajan | April 4, 2013

New sequencing technologies are largely funded with the hope that the next technology will take sequencers into the diagnostics world. This requires overcoming two present hurdles: cost per base and turnaround time. At the Advances in Genome Biology and Technology conference held at Marco Island, 2012, Oxford Nanopore Technologies introduced its USB size sequencer ‘MinION’,…

Exploring The Frontiers: An Introduction to Metagenomics

By Aparna Natarajan | January 31, 2013

Why Metagenomics? The microorganisms that we know and understand today are the ones which either cause human diseases, or are beneficial to human society in some way. From wine and cheese in food industry to the pharmaceutical industry- they are an indispensable part of our lives. Despite making good progress in understanding the microbial world,…

NGS in clinical diagnostics

By Aparna Natarajan | November 15, 2012

Thirty-five years ago, Dr. Janet Davison Rowley sat at a microscope in her lab at the University of Chicago and made a remarkable discovery in cancer biology, that leukemia is caused by the translocation of a chromosome. In other words, it is a disease of the DNA. Today, thanks to next generation sequencing (NGS), we can zoom in…

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