Chromatin Immunoprecipitation (ChIP) is a powerful technique for evaluating the interactions of proteins with specific regions of genomic DNA, helping to better understand the mechanisms such as, gene regulation, DNA replication, repair and recombination, and epigenetic silencing. The use of ChIP in conjunction with NGS (ChIP-Seq) has enabled wide scale application of this technique to [...]

For decades, investigators have considered type 1 diabetes (T1D) a disease whose development was influenced in large part by the environment. While many environmental influences have been posited for their putative association with the disease, none have seen more interest and supporting data than viruses (in general) and enteroviruses (in particular). The reasons underlying a [...]

Whether it’s an informal poster, journal club or chalk talk or a more formal thesis, job talk or seminar, every scientist is expected to give presentations at all stages of their career. For many scientists, communicating their work generates great fear, whether because of a perceived handicap in presentation skills and knowledge or a lack [...]

There’s a clear correlation between the benefits of public relations and successful business endeavors, whether in private industry or not-for-profit philanthropy. In addition to creating publicity buzz and sharing newsworthy accomplishments, a good public relations (PR) strategy acts as an important gateway for gaining widespread recognition within a field or area of expertise. The value [...]

In this seminar, we explore the power of selectivity using the resolution equation in HPLC and UHPLC. Using a variety of chromatographic data, we discuss how incorporating an aromatic building block in phase design has led to the unique bonded phases ACE® C18-AR and ACE® C18-PFP. These unique phases have been engineered based upon the popular [...]

In research, protocol consistency is a key element for ensuring the results you get are valid. You need to be sure that experimental results can be replicated, and that conditions are kept consistent with each repetition. Unfortunately, in many labs protocols are not standardized and methods are not transparent, leading to differences in the way [...]

Leica Microsystems recently introduced their next generation of confocal, the Leica TCS SP8 – a truly configurable platform that allows you to create your confocal exactly as you need it. As your scientific research develops further, so you need a system that evolves, adapts and reconfigures. What you discover today will be the foundation of [...]

HPLC separations of biomolecules have traditionally required much time in order to achieve the required resolution for complex samples. However, this has recently begun to change with the developments that have been made in Fused-Core particle technology. HPLC columns of high purity silica that are 2.7 µm in total particle size with a 0.5 µm [...]

Congratulations! If you are reading this, it means that you are either a newly minted assistant professor, or well on your way towards becoming one. Running your lab is an exciting venture, filled with success, discovery, and the opportunity to pursue novel research of your own. With such excitement also comes great responsibility, in tasks [...]

It does not matter if you’re a grad student, a postdoc, the PI or the lab manager; if you’re a researcher you know dealing with experimental data, specimens, protocols and more is never an easy task. We’re scientists, right? Aren’t we supposed to be doing science, instead of worrying about tedious managerial and administrative tasks? [...]