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Why DNA Size Selection Matters in NGS Pipelines

Of all the sample prep steps necessary for next generation sequencing, DNA size selection may have the greatest impact on quality of results. After all, ineffective sizing can waste sequencing capacity on low molecular weight material such as adapter-dimers or primer-dimers, while imprecise sizing can prevent bioinformaticians from producing accurate assemblies. High-quality size selection can […]

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In Genomics & Epigenetics, Sage Science 15th of January, 2016