Dan

Dan is a postdoc working at the University of Cyprus in developmental biology. He has a BSc in molecular biology and a PhD pharmacology and biochemistry.

Articles by Dan:

Cells – This Side Up

Perhaps the most fundamental aspect of migration of any kind is, how do you know which way to point yourself? Heck, this isn’t just about migration, it’s about how something is oriented in its immediate environment. For orientation, there’s magnetic North, gravity, or any conceivable cue that you might choose to face towards. How do…

31 Oct 2007 Of Interest

Arthur Kornberg, Biochemist

In memorandum of one of the pioneers of molecular biology, who was awarded a Nobel Prize in medicine for the discovery of DNA polymerase. What molecular biology blog would this be if we didn’t honor his memory? Larry Moran presents a fine eulogy, as does the NYTimes: Dr. Arthur Kornberg, a biochemist whose Nobel Prize-winning…

30 Oct 2007 History of Biology

IRESs and Negative Data

Nature Precedings represents a step forward for disseminating experimental results in the internet age. Especially ‘negative’ results, that might not have gotten published otherwise, but is extremely helpful to other researchers in trying to avoid making the same mistakes. Refutation of a hypothesis, while not a discovery, is the goal of the well-planned experiment in…

29 Oct 2007 Of Interest

Around the Blogs

10 links to some popular blogs of the molecular and cellular biosciences: Bacillus? Acinetobacter? Thermus?!? – Rosie takes us through her thought process in developing an experiment on growth conditions, while she considers what organism to use. These Cells are Left-Handed – Some comments on the influence of chirality on cell polarity. Chlamydomonas Swims Across…

26 Oct 2007 Of Interest

Open Access to Science

The Public Library of Science (PLoS) defines the issue of Open Access Publication as: An Open Access Publication[1] is one that meets the following two conditions: 1. The author(s) and copyright holder(s) grant(s) to all users a free, irrevocable, worldwide, perpetual right of access to, and a license to copy, use, distribute, transmit and display…

25 Oct 2007 Taming the Literature

History of Molecular Biology

As a freshman biology major in undergrad, I was introduced to molecular biology with the following description: Molecular biology represents the intersection of genetics, biochemistry and cell biology. Some people, it turns out, add microbiology and virology into the mix. So molecular biology is often used as a catch-all, to describe a wide breadth of…

24 Oct 2007 DNA / RNA Manipulation and Analysis

Histone Methylation Determines Cell Fate

Gene expression is controlled at all sorts of levels in eukaryotic cells, and one of the hot areas is that of histone modifications and how they influence transcriptional accessibility on chromosomes – epigenetic regulation, as it’s called. Think of it as an analog annotation system for the cell’s genome, where each gene is wrapped up…

23 Oct 2007 Of Interest

Modeling Tertiary Structure

Predicting and modeling protein structure, making protein crystallography somewhat obsolete, has been an elusive science to date. Since Linus Pauling and others determined that the most favorable secondary structures are the alpha helix and beta sheet, molecular and structural biologists have sought a set of rules with which to predict a protein’s structure from its…

22 Oct 2007 Of Interest