How Stuff Works

How Stuff Works

How is Lab Grade Water Purified?

There's something in the water, and it would love to go after your experiments. Straight out of [read more]

How Stuff Works

How Thermophiles Survive, Part II: DNA

In part I, I answered the question, "How do proteins in thermophiles survive under high [read more]

How Stuff Works

The Secrets of Thermophile Survival: Part I

In response to my last article, The Taq behind PCR, one of our readers, Bonnie Barrilleaux, asked [read more]

How Stuff Works

RPM Does Not Equal RCF

RPM and RCF are two units that can be used to describe the speed of a centrifuge. Although they may [read more]

How Stuff Works

Plasmid v Genomic DNA Extraction:The Difference

If you want to isolate plasmid DNA, you crack your cells open and carry out a miniprep, trying very [read more]

How Stuff Works

5 Laboratory Sterilisation Methods

Effective sterilisation techniques are essential for working with isolated cell lines for obvious [read more]

How Stuff Works

How SDS-PAGE works

SDS-PAGE (sodium dodecyl sulphate-polyacrylamide gel electrophoresis) is commonly used in the lab [read more]

How Stuff Works

The Basics: How Phenol Extraction Works

Phenol extraction is a commonly used method for removing proteins from a DNA sample, e.g. to remove [read more]

How Stuff Works

Enzyme Commission (EC) Numbers

In the early 1950's so many new enzymes were being discovered in the burgeoning field of [read more]

How Stuff Works

The Basics: How Alkaline Lysis Works

Alkaline lysis was first described by Birnboim and Doly in 1979 (Nucleic Acids Res. 7, 1513-1523) [read more]

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