Soft Skills & Tools / Lab Statistics & Math

Soft Skills & Tools / Lab Statistics & Math
Article

How to perform cell synchronization in specific cell cycle phases

The cell cycle has been very well documented over the years because of its dysregulation in diseases such as cancer. Many different processes contribute to cell growth and replication, which is ultimately...
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Article

Analyze Immunostained Slides with Semiquantitative Scoring

A  routine task in the lab is to investigate the presence of your favorite protein in a range of histological samples. No doubt, staining your tissue sections using good old immunohistochemistry (IHC) would be...
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Size-Selection Is Essential for Cell-Free DNA Studies

Advances in using cell-free DNA (cfDNA) to glean clinically meaningful information for a patient have been stunning. For the most part, these research studies (or downstream diagnostic tests) isolate fetal DNA...
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Troubleshooting Surface Plasmon Resonance: Resolving Non-Specific Binding, Regeneration and Other Problems

Surface plasmon resonance (SPR), a label-free, real-time way to examine protein binding and other molecular interactions, is getting easier as manufacturers have streamlined SPR instruments and supporting...
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Article

Mysterious miRNA: Identifying miRNAs and Their Targets

In my first article on this topic we delved into what miRNAs are, how they are generated, and their function. Now, we are going to discuss how to identify miRNAs and their targets. Why do you want to look at...
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Article

How Many Data Points Do I Need For My Experiment?

To draw a convincing conclusion from your data, you cannot simply shoot for the standard significance cutoff. You also need to consider the statistical power, which is determined in part by the sample size in your experiment.
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Article

Statistics for Biologists: Chi Square Test and its use in Biology

Statistics is one of the most hated subjects by biologists around the globe. In spite of its daily dose of abuse, knowledge of statistics can be a life-saver. Chi square distribution and test is one of the...
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Article

Choose the Statistical Package that Will Make Your Data Talk

In the last years, the need for using statistical testing in bioscience has grown exponentially and so has the development of statistical software. It is now common that everyone is using some sort of stats in...
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Article

3 Common Myths About p Value: Alternatively Never, Ever Rely on it for Data Interpretation

When it comes to data analysis and interpretation, you need to be very clear about the meaning of a given p value and be aware of all its intrinsic limitations.
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Article

How to Choose a PhD Topic

Choosing a PhD topic can be very hard. There are a lot of things to consider from the subject to the supervisor. Here are some tips to help you choose. Find out what you really like This is the first topic...
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