Basic Lab Skills & Know-how

Shaky, Steady, Go! Give Tremors the Shake

Performing a surgery or extracting tissue from your experimental animal, when you are a beginner, can set you off with involuntary trembling. Strong dyskinesia symptoms appear out of nowhere. The shaking can hinder your otherwise flawless execution of the task. And yes, it’s irritating that it occurs precisely at the moment when you need your…

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Hot, Frozen, Sublimed and Blown: Biological Sample Storage Methods Summarized – Part One

I’ve recently been doing some lyophilization of biological extracts. While I was preparing for the experiment, I became interested in the number of different methods there are for drying, concentrating and storing samples: freezing, freeze-drying, rotary evaporation, centrifugal evaporation and blow down drying. Here is a brief description of each technique for biological sample storage…

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How to Clean and Maintain Scales

Spring time means spring cleaning! Baby birds are hatching, the days are getting longer, there are butterflies everywhere and you feel inspired to do a good deep clean of your lab scales. We can’t help you sing like Snow White so that animals come help you clean but we can help you get your scales…

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6 Common Lab Uses of Detergents

Detergents are all around us in the lab – and that’s a good thing! Thanks to their chemical structure, detergents can solubilize and interact with many types of molecules, making them vital to research. To show you why detergents are such a good thing for scientists, we’ll go through six examples in molecular biology where…

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A Quick Guide to pH, pKa and pI

They’re easy numbers to take for granted, so it’s a good exercise once in a while to remind ourselves what pH, pKa and pI stand for: pH—the measure of acidity. It’s the negative logarithm of the proton concentration. pKa—an association constant. It’s the negative logarithm of the ratio of dissociated acid and conjugated base, over…

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