Soft Skills & Tools

Article

How to perform cell synchronization in specific cell cycle phases

The cell cycle has been very well documented over the years because of its dysregulation in diseases such as cancer. Many different processes contribute to cell growth and replication, which is ultimately...
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Article

Analyze Immunostained Slides with Semiquantitative Scoring

A  routine task in the lab is to investigate the presence of your favorite protein in a range of histological samples. No doubt, staining your tissue sections using good old immunohistochemistry (IHC) would be...
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Article

ChemDraw: a Versatile Molecule Sketching Tool for (Bio)Chemists

Have you ever wondered how to make professional, easy-to-understand figures of molecules for presentations or publications? While several programs exist for this purpose, ChemDraw is like the Swiss Army knife...
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Article

Drift in Measurements with Analytical Balances

Pharmaceutical laboratories and bioscience research institutes make extensive use of analytical balances that are highly sensitive. These analytical balances are greatly affected by their environment and also...
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Size-Selection Is Essential for Cell-Free DNA Studies

Advances in using cell-free DNA (cfDNA) to glean clinically meaningful information for a patient have been stunning. For the most part, these research studies (or downstream diagnostic tests) isolate fetal DNA...
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Article

Water your choices? Understanding Types of Water in the Lab

If you are working in a scientific laboratory, it is very important to be aware of the various types of water available, because the purity may not be acceptable for your specific experimental...
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Article

Investigating an Expression Quantitative Trait Locus (eQTL)

Thousands upon thousands of genetic variants are now associated with every disease and trait you can possibly think of. Such traits range from cancers to blood pressure, intelligence, height, weight… and many...
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Article

Running your Lab on a Shoestring Budget

We live in challenging times for academic biomedical research. The success rates for research grants have declined precipitously over the years. Under these circumstances, it is never too soon to take proactive...
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Article

How to Pour Agar Plates in a Pinch

Every lab has a culture, a vibe of its own. Nowhere does the distinct character of the lab become most apparent than the way in which the lab chooses to pour agar plates. You may have heard or been told to pour...
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Article

Outsourcing Research: Should Your Experiment Spend Some Time Away from You?

As a researcher, it’s satisfying to manage your own projects and do the bench work yourself. After all, if you don’t have experience with a technique, you’re usually expected to figure it out (with or...
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