Archive for the ‘Journal Club’ Category

Metabolism as Biogenesis

by Dan on January 30, 2008
One of the several popular views regarding the origin of life stems from thermodynamics. Harold Morowitz refers to it as "Metabolism recapitulates biogenesis". In PLoS Biology there's an interesting essay that was submitted (read on...)

Geometries of Cells

by Dan on January 29, 2008
Form follows physics in the fly eye, say Sascha Hilgenfeldt, Sinem Erisken, and Richard Carthew Simple forces, complex shapes: While most biological features appear complex in their geometries and varieties of components, (read on...)

Kinase Structures and Autoinhibition

by Dan on January 3, 2008
Here's a comment on work published about 6 months ago that was relevant to me, given my graduate studies on FAK with Jun-Lin Guan. The relations between protein structures and evolution are quite interesting indeed. As more (read on...)

Relating to Historical Contingency in Biology

by Dan on January 2, 2008
Two blog posts recently collided for me. First, in a blog discussion on Macroevolution vs. Microevolution, Allen MacNeill clarified some issues for me (thanks to TUIBG for bringing it back up): Add the newly emerging fields of (read on...)

The Big Story of 2007: Cellular Alchemy

by Dan on December 19, 2007
Amid the political controversy and obstructions to conducting stem cell research, scientists this year managed to turn lead into gold... Genetically manipulating fibroblasts to become ESC(embryonic stem cell)-like sort of sounds (read on...)

Protein Sociology: Collective Interaction Behaviors

by Dan on December 13, 2007
As always, it's these odd conjunctions of things that don't go together that catches the eye. In this case, molecular and sociology. The actual article1 is much more mundane and true to the correct science jargon, and included (read on...)

Battling Disease – The Real-Life Hydra?

by Terry on December 13, 2007
A recent article in Science discussed a claim made by Bill and Melinda Gates, where they proposed that malaria could be eradicated from the Earth over the next few decades. Vanquishing disease is seen as the ultimate goal in (read on...)

Thinking Microbes

by Dan on December 10, 2007
Cognition is a term frequently used in several loosely related ways to refer to a faculty for the human-like processing of information. Signal transduction networks certainly fit that bill, as the mediate adaptive changes in (read on...)

Myosin Isoforms: Duplication and Divergence

by Dan on December 6, 2007
Myosin II functions as a molecular motor which facilitates contraction of the actin cytoskeleton during migration, resides outside of protrusions at the front of motile cells, and acts at a distance to impact cell protrusion, (read on...)

miRNAs Get Flipped

by Dan on December 4, 2007
On a couple other blogs, a study published in Science by Joan Steitz1 is being called "One of the biggest findings of the year," and "If it turns out to be true, this finding just flipped the whole field on its head." Bitesize (read on...)

Bites from the Archive