What Can NMR Do For You? — Part Two

Welcome to part two of “What Can NMR Do For You?”, a three-part series in which we see how you can use simple NMR experiments in your research. In part one, we went over […]

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How Do YOU Stain Your DNA?

Visualization of DNA in gels is one of the most common procedures a molecular biologist can perform.  In a good day, I can run at least 4 different DNA gels!  When I was trained, […]

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Garbage in, Garbage out? Quality Control of Your NGS Data

So you’ve just received a call from the core facility you hired to prepare and sequence your libraries. The facility director tells you that the sequence data does not look good. You panic- aaarrrrggghhhh! […]

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Could Crowd-Funding Work In Science?

In times of financial crisis, as we are currently experiencing, some governments think that it’s OK, or even wise, to cut down on funding for scientific research. Even though we know better, we are […]

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Rubbing Your Microscope’s Eyes: A Guide to Optical Resolution

Ever wake up especially groggy in the morning, finding it takes a few minutes and a few eye rubs to be able to decipher the numbers on your alarm clock? Our eyes have the […]

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10 Uses for a PhD Thesis

Earning a PhD is something to be proud of. It represents years of hard work and an original contribution to science. And yet, the main product of this labor is a very large, rather […]

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Book Review: “The Double Helix”, by James Watson

Is it just me, or are there not many well-written scientific memoirs around? Even the words “scientific memoir” brings up an image of a long and boring book. There are a lot of good […]

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You’re Closer to the Clinic Than You Think: NGS and Clinical Trials

A decade or so ago, the phrase ‘translational research’ began making its rounds through laboratories- it was supposed to take molecular biology results and apply them directly to patients. It brought about things like […]

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The Advanced User’s Guide to Sequencing Alignment Software (Members Only Article)

Whether you’re employing sequencing gels, Sanger-based methods, or the latest in pyrosequencing or ion torrent technologies, obtaining, manipulating and analyzing your sequences has never been easier. Depending on what your goals are, you need […]

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Tissue Embedding and Sectioning: Something to Think About Whilst in the Bath.

In the same way that you should ‘Think Before You Fix’, the choice of embedding media should be dictated by your required end-point. The basic principle is that by processing tissue into an embedding […]

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